Date published: 2026-4-4

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Conjugated Estrogen (CAS 12126-59-9)

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Application:
Conjugated Estrogen is a mixture of estrogen derivatives-mostly estrone and equilin sulfate
CAS Number:
12126-59-9
Purity:
≥85%
Molecular Weight:
370.39
Molecular Formula:
C18H19NaO5S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Conjugated estrogen is a compound that is extensively studied for its biological properties and interactions with estrogen receptors in various tissues. It is used in research to understand the signaling pathways and gene expression profiles modulated by estrogenic compounds. Studies often explore the role of conjugated estrogen in regulating reproductive tissues, bone density, and cardiovascular health at the cellular and molecular levels. In addition, researchers utilize this compound to investigate the effects of estrogen on the central nervous system, including cognitive functions and neuroprotection. The compound′s influence on lipid metabolism and the mechanisms underlying its impact on cholesterol levels are also areas of active investigation. Furthermore, conjugated estrogen is used in comparative studies to analyze the differential effects of various estrogenic substances on cellular proliferation and differentiation.


Conjugated Estrogen (CAS 12126-59-9) References

  1. Conjugated estrogen administration improves common carotid artery elastic properties in normotensive postmenopausal women.  |  Kallikazaros, I., et al. 2002. Clin Cardiol. 25: 167-72. PMID: 12000074
  2. Estrogen replacement therapy for Alzheimer disease in postmenopausal women.  |  Owens, CT. 2002. Ann Pharmacother. 36: 1273-6. PMID: 12086563
  3. Conjugated estrogen/bazedoxifene tablets for the treatment of moderate-to-severe vasomotor symptoms associated with menopause.  |  Mirkin, S., et al. 2014. Womens Health (Lond). 10: 135-46. PMID: 24601804
  4. Management of postmenopausal osteoporosis and the prevention of fractures.  |  Gambacciani, M. and Levancini, M. 2014. Panminerva Med. 56: 115-31. PMID: 24942322
  5. Preclinical breast effects of a tissue selective estrogen complex (TSEC) including conjugated estrogen with bazedoxifene.  |  Santen, RJ., et al. 2017. J Steroid Biochem Mol Biol. 170: 61-64. PMID: 27174719
  6. Conjugated Estrogen in Late-Onset Hemorrhagic Cystitis Associated with Hematopoietic Stem Cell Transplantation.  |  Mousavi, SA., et al. 2017. Int J Hematol Oncol Stem Cell Res. 11: 13-18. PMID: 28286609
  7. Tissue-selective Estrogen Complex for Menopausal Hormone Therapy.  |  Pinkerton, JV. 2018. Clin Obstet Gynecol. 61: 463-469. PMID: 29851863
  8. Application of conjugated estrogen cream in the treatment of postmenopausal atrophic vaginitis.  |  Li, D. and Bai, W. 2018. Pak J Pharm Sci. 31: 2283-2286. PMID: 30463825
  9. Effects of conjugated estrogen and bazedoxifene on hemostasis and thrombosis in mice.  |  Noirrit, E., et al. 2019. Endocr Connect. 8: 788-795. PMID: 31085766
  10. The Microbiome-Estrogen Connection and Breast Cancer Risk.  |  Parida, S. and Sharma, D. 2019. Cells. 8: PMID: 31847455
  11. Investigation of free and conjugated estrogen fate and emission coefficients in three duck farms.  |  Hung, HS., et al. 2023. Environ Sci Pollut Res Int. 30: 9874-9885. PMID: 36059016
  12. Effects of varying doses of conjugated estrogen on body weight, hormonal and histological alterations of reproductive organs in adult swiss albino female mice.  |  Alam, M., et al. 2023. Heliyon. 9: e15112. PMID: 37095990
  13. Bioequivalence of conjugated estrogen products.  |  Ansbacher, R. 1993. Clin Pharmacokinet. 24: 271-4. PMID: 8387902

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Conjugated Estrogen, 25 mg

sc-357319
25 mg
$153.00

Conjugated Estrogen, 100 mg

sc-357319A
100 mg
$468.00