Compound 34
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Compound 34 is a chemical that functions as a potent inhibitor of the target protein. It binds to the active site of the protein, disrupting its normal function and preventing the catalysis of key biochemical reactions. This inhibition leads to a cascade of downstream effects within the cellular pathway under investigation. The compound′s mode of action involves interfering with the protein′s ability to interact with its substrates, ultimately impeding the progression of the biochemical pathway. This disruption at the molecular level gains insights into the specific role of the target protein in the context of the cellular process being studied. Compound 34′s activity as an inhibitor provides function of the target protein and its involvement in the broader biological system. I
Compound 34 References
- Discovery of oral and inhaled PDE4 inhibitors. | Ting, PC., et al. 2013. Bioorg Med Chem Lett. 23: 5528-32. PMID: 24018187
- α-Substituted 2-(3-fluoro-4-methylsulfonamidophenyl)acetamides as potent TRPV1 antagonists. | Tran, PT., et al. 2015. Bioorg Med Chem Lett. 25: 2326-30. PMID: 25937016
- Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents. | Kaushik-Basu, N., et al. 2016. Eur J Med Chem. 122: 319-325. PMID: 27376494
- Evaluation of antifungal activities and structure-activity relationships of coumarin derivatives. | Song, PP., et al. 2017. Pest Manag Sci. 73: 94-101. PMID: 27570117
- Structure-Based Design of 1-Heteroaryl-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists. | Peng, P., et al. 2018. J Med Chem. 61: 9621-9636. PMID: 30234300
- Novel amide derivatives containing 1,3,4-thiadiazole moiety: Design, synthesis, nematocidal and antibacterial activities. | Chen, J., et al. 2019. Bioorg Med Chem Lett. 29: 1203-1210. PMID: 30902458
- Development of Small-Molecules Targeting Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-Receptor Activator of Nuclear Factor-κB (RANK) Protein-Protein Interaction by Structure-Based Virtual Screening and Hit Optimization. | Jiang, M., et al. 2019. J Med Chem. 62: 5370-5381. PMID: 31082234
- Discovery of novel pyrrolo[2,3-b]pyridine derivatives bearing 4-oxoquinoline moiety as potential antitumor inhibitor. | Liu, H., et al. 2020. Bioorg Med Chem Lett. 30: 126848. PMID: 31836443
- Novel [1,2,3]triazolo[4,5-d]pyrimidine derivatives containing hydrazone fragment as potent and selective anticancer agents. | Xu, C., et al. 2020. Bioorg Chem. 105: 104424. PMID: 33161253
- Selenium-Containing Compound Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via Regulating the MAPK/AP-1 Pathway. | Jia, W., et al. 2021. Inflammation. 44: 2518-2530. PMID: 34487287
- Discovery of Pyrido[1,2-a]pyrimidinone Mesoionic Compounds Incorporating a Dithioacetal Moiety as Novel Potential Insecticidal Agents. | Zhang, J., et al. 2021. J Agric Food Chem. 69: 15136-15144. PMID: 34878774
- Pharmacokinetic/Pharmacodynamic Evaluation of a New Purine-2,6-Dione Derivative in Rodents with Experimental Autoimmune Diseases. | Świerczek, A., et al. 2022. Pharmaceutics. 14: PMID: 35631676
- Discovery of pyrido[4,3-d]pyrimidinone derivatives as novel Wee1 inhibitors. | Ye, Q., et al. 2023. Bioorg Med Chem. 87: 117312. PMID: 37167712
- Design and synthesis of novel PPO-inhibiting pyrimidinedione derivatives safed towards cotton. | Wu, X., et al. 2023. Pestic Biochem Physiol. 193: 105449. PMID: 37248018
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Compound 34, 200 µg | sc-391108 | 200 µg | $84.00 | |||
Compound 34, 1 mg | sc-391108A | 1 mg | $270.00 |