Molecular structure of Compound 112254, CAS Number: 949745-75-9
Compound 112254 (CAS 949745-75-9)
Alternate Names:
4-(tert-Butyl)-N-(3-(4-(4-methoxybenzyl)piperazin-1-yl)-3-oxopropyl)benzamide
Application:
Compound 112254 is an adiponectin receptor (AdipoR) agonist
CAS Number:
949745-75-9
Molecular Weight:
437.57
Molecular Formula:
C26H35N3O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Compound 112254 is an AdipoR (adiponectin receptor) agonist and binds to AdipoR1 and AdipoR2. Compound 112254 activates AMPK (5'-adenosine monophosphate-activated protein kinase) in cultured mammalian cells.
Compound 112254 (CAS 949745-75-9) References
- A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity. | Okada-Iwabu, M., et al. 2013. Nature. 503: 493-9. PMID: 24172895
- Modulation of adiponectin receptors AdipoR1 and AdipoR2 by phage display-derived peptides in in vitro and in vivo models. | Crombez, D., et al. 2020. J Drug Target. 28: 831-851. PMID: 31888393
Activator of:
AdipoR, and AMPK.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Compound 112254, 10 mg | sc-396660 | 10 mg | $105.00 | |||
Compound 112254, 50 mg | sc-396660A | 50 mg | $410.00 |