COLO 205 Whole Cell Lysate: sc-364177

The COLO 205 Whole Cell Lysate is prepared from the COLO 205 cell line, which originates from a human colorectal adenocarcinoma. The lysate contains a comprehensive array of cellular components, including proteins, nucleic acids, lipids, and metabolites, extracted using rigorous cell disruption techniques such as sonication, enzymatic digestion, or detergent-based lysis. This cell line and its derived lysate are frequently utilized in non-medical research to study the fundamental aspects of colorectal cell biology, such as cellular response mechanisms to environmental stimuli or the internal signaling pathways that govern cell survival and proliferation. The COLO 205 Whole Cell Lysate serves as a valuable resource for researchers interested in the proteomics field, allowing them to carry out protein profiling and interaction studies, which are essential for understanding the complex protein networks within colorectal cells. Additionally, this lysate contributes to studies focused on gene expression and regulation within cancer cells, supporting broader scientific inquiries into cellular morphology and genetics without any clinical or therapeutic intent. By providing a snapshot of the cellular makeup of colorectal adenocarcinoma cells, the COLO 205 Whole Cell Lysate aids in advancing knowledge on fundamental cellular processes and molecular biology in an exclusively research-based context.

COLO 205 Whole Cell Lysate References:

1. Selectin ligand expression regulates the initial vascular interactions of colon carcinoma cells: the roles of CD44v and alternative sialofucosylated selectin ligands.  |  Napier, SL., et al. 2007. J Biol Chem. 282: 3433-41. PMID: 17135256
2. Hematogenous metastasis: roles of CD44v and alternative sialofucosylated selectin ligands.  |  Konstantopoulos, K. and Thomas, SN. 2011. Adv Exp Med Biol. 705: 601-19. PMID: 21618132