Collectin 43 Antibody (260-04): sc-59149

Collectin 43 Antibody (260-04) is a mouse monoclonal IgG1 antibody that detects Collectin 43 in bovine samples through western blotting (WB). Collectin 43 is a crucial component of the innate immune system in cows, functioning as a C-type serum lectin that plays a significant role in the defense against viral, fungal, and bacterial pathogens. Collectin 43 is synthesized in the liver and is composed of three identical chains, each featuring a collagen region and a C-type carbohydrate recognition domain, which allows binding to microbial surface carbohydrates in a calcium-dependent manner. Anti-Collectin 43 antibody (260-04) enables detection of both native and truncated isoforms, which can aggregate pathogens to impede infectivity and facilitate phagocytosis by immune cells, highlighting Collectin 43′s importance in maintaining bovine health. The presence of two isoforms suggests complexity in function and variability in serum levels, which may be linked to various diseases in cows. Collectin 43 (260-04) antibody serves as an essential tool for researchers studying immune responses in bovine species and Collectin 43′s implications in veterinary health.