Molecular structure of Colistin sulfate, CAS Number: 1264-72-8
Colistin sulfate (CAS 1264-72-8)
See product citations (7)
Alternate Names:
Belcomycin; Polymixin E Sulfate
Application:
Colistin sulfate is a Polymyxin potent antibiotic and apoptosis inducer
CAS Number:
1264-72-8
Purity:
Mixture of >30 compounds, primarily colistin A and B
Molecular Weight:
1267.55
Molecular Formula:
C53H102N16O17S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Colistin sulphate is a compound that is used primarily in research applications to study bacterial resistance mechanisms and the effects of antibiotics on bacterial growth. In microbiological research, colistin sulphate serves as a selective agent for certain types of bacteria due to its effectiveness against Gram-negative organisms, particularly Pseudomonas aeruginosa. It is also used to investigate the permeability of bacterial outer membranes and the role of lipopolysaccharides in providing resistance to antibiotics. In environmental studies, colistin sulphate is employed to analyze the presence and spread of antibiotic-resistant genes in different ecosystems.
Colistin sulfate (CAS 1264-72-8) References
- Polymyxin B sulfate and colistin: old antibiotics for emerging multiresistant gram-negative bacteria. | Evans, ME., et al. 1999. Ann Pharmacother. 33: 960-7. PMID: 10492501
- Isolation and structural characterization of colistin components. | Orwa, JA., et al. 2001. J Antibiot (Tokyo). 54: 595-9. PMID: 11560379
- The clinical use of colistin in patients with cystic fibrosis. | Beringer, P. 2001. Curr Opin Pulm Med. 7: 434-40. PMID: 11706322
- Polymyxin E-1 (colistin sulphate) (neuro-)intoxication in young ostriches (Struthio camelus spp.). | Landman, WJ., et al. 2000. Avian Pathol. 29: 593-601. PMID: 19184856
- Simultaneous quantitation of tobramycin and colistin sulphate by HPLC with evaporative light scattering detection. | Clarot, I., et al. 2009. J Pharm Biomed Anal. 50: 64-7. PMID: 19372021
- Colistin powders with high aerosolisation efficiency for respiratory infection: preparation and in vitro evaluation. | Zhou, QT., et al. 2013. J Pharm Sci. 102: 3736-47. PMID: 23904207
- Study on anaerobic digestion treatment of hazardous colistin sulphate contained pharmaceutical sludge. | Yin, F., et al. 2015. Bioresour Technol. 177: 188-93. PMID: 25490101
- Colistin sulphate induced neurotoxicity: Studies on cholinergic, monoaminergic, purinergic and oxidative stress biomarkers. | Ajiboye, TO. 2018. Biomed Pharmacother. 103: 1701-1707. PMID: 29864960
- Comparison of the binding of gram-negative bacterial endotoxin by polymyxin B sulphate, colistin sulphate and colistin sulphomethate sodium. | Rogers, MJ. and Cohen, J. 1986. Infection. 14: 79-81. PMID: 3011678
- Plant chemical genetics reveals colistin sulphate as a SA and NPR1-independent PR1 inducer functioning via a p38-like kinase pathway. | Halder, V., et al. 2019. Sci Rep. 9: 11196. PMID: 31371749
- Intraventricular colistin sulphate as a last resort therapy in a patient with multidrug-resistant Acinetobacter baumannii induced post-neurosurgical ventriculitis. | Yu, XB., et al. 2022. Br J Clin Pharmacol. 88: 3490-3494. PMID: 35060164
- In vitro inhibition of the classical pathway of human complement by a natural microbial product, colistin sulphate. | Asghar, SS., et al. 1986. Biochem Pharmacol. 35: 2917-21. PMID: 3638137
- Antibacterial action of colistin (polymyxin E) against Mycobacterium aurum. | David, HL. and Rastogi, N. 1985. Antimicrob Agents Chemother. 27: 701-7. PMID: 4015067
- Colistin sulphate in the treatment of specific bacterial intestinal infections. | Lamb, R. 1968. Scott Med J. 13: 9-12. PMID: 4865523
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Colistin sulfate, 500 mg | sc-204696 | 500 mg | $166.00 |