Molecular structure of Colistin sodium methanesulfonate, CAS Number: 8068-28-8
Colistin sodium methanesulfonate (CAS 8068-28-8)
See product citations (1)
Alternate Names:
Colimycin sodium methanesulfonate; Methanesulfonic acid derivative of Polymyxin E; Polymyxin E sodium methanesulfonate
Application:
Colistin sodium methanesulfonate is Colistin sodium methanesulfonate is a cyclopolypeptide antibiotic and derivative of Polymyxin E.
CAS Number:
8068-28-8
Molecular Weight:
1759.90
Molecular Formula:
C58H115N16O28S5•5Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Colistin sodium methanesulfonate binds to lipids on the cell cytoplasmic membrane of Gram-negative bacteria and disrupts the cell wall integrity. Antimicrobial spectrum: Gram-negative bacteria. Cyclopolypeptide antibiotic. Endotoxin-binding capacity.
Colistin sodium methanesulfonate (CAS 8068-28-8) References
- Polymyxins as novel and safe mucosal adjuvants to induce humoral immune responses in mice. | Yoshino, N., et al. 2013. PLoS One. 8: e61643. PMID: 23593492
- Effect of sub-minimum inhibitory concentrations of ciprofloxacin, amikacin and colistin on biofilm formation and virulence factors of Escherichia coli planktonic and biofilm forms isolated from human urine. | Wojnicz, D. and Tichaczek-Goska, D. 2013. Braz J Microbiol. 44: 259-65. PMID: 24159313
- Localization of gonococcal lipopolysaccharide and its relationship to toxic damage in human fallopian tube mucosa. | Cooper, MD., et al. 1986. Infect Immun. 51: 425-30. PMID: 2417954
- Polymyxins for the treatment of extensively-drug-resistant Gram-negative bacteria: from pharmacokinetics to bedside. | Zavascki, AP. 2014. Expert Rev Anti Infect Ther. 12: 531-3. PMID: 24666285
- Combination of pipemidic acid, colistin sodium methanesulfonate and nystatin may be less effective than nystatin alone for prevention of infection during chemotherapy-induced granulocytopenia in acute leukemia. | Sampi, K., et al. 1989. Med Oncol Tumor Pharmacother. 6: 291-6. PMID: 2615532
- Characterization of urinary metabolites as biomarkers of colistin-induced nephrotoxicity in rats by a liquid chromatography/mass spectrometry-based metabolomics approach. | Jeong, ES., et al. 2016. Toxicol Lett. 248: 52-60. PMID: 26947560
- Conjunctivitis Caused by a Strain of Neisseria gonorrhoeae That Was Less Susceptible to Ceftriaxone. | Iwata, A., et al. 2017. Intern Med. 56: 1443-1445. PMID: 28566614
- Interaction of Bacterial Phenazines with Colistimethate in Bronchial Epithelial Cells. | Mossine, VV., et al. 2018. Antimicrob Agents Chemother. 62: PMID: 29784845
- Role of Viscoelasticity in Bacterial Killing by Antimicrobials in Differently Grown Pseudomonas aeruginosa Biofilms. | Rozenbaum, RT., et al. 2019. Antimicrob Agents Chemother. 63: PMID: 30745390
- Safety of topical ophthalmic antibiotics in pregnant women with hordeola, chalazia, blepharitis, or bacterial conjunctivitis: propensity score analyses. | Hashimoto, Y., et al. 2022. Eye (Lond). 36: 1066-1073. PMID: 34035495
- Seaweed Extracts: A Promising Source of Antibiofilm Agents with Distinct Mechanisms of Action against Pseudomonas aeruginosa. | Rima, M., et al. 2022. Mar Drugs. 20: PMID: 35200622
- Omeprazole Prevents Colistin-Induced Nephrotoxicity in Rats: Emphasis on Oxidative Stress, Inflammation, Apoptosis and Colistin Accumulation in Kidneys. | Nasrullah, MZ., et al. 2022. Pharmaceuticals (Basel). 15: PMID: 35890080
- Prevalence of classes 1 and 2 integrons in multidrug-resistant Acinetobacter baumanni isolates recovered from some aquatic environment in South Africa. | Adeniji, OO., et al. 2022. Sci Rep. 12: 20319. PMID: 36434075
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Colistin sodium methanesulfonate, 1 g | sc-252624 | 1 g | $147.00 |