Date published: 2026-4-25

1-800-457-3801

SCBT Portrait Logo
Seach Input

Colchicoside (CAS 477-29-2)

0.0(0)
Write a reviewAsk a question

CAS Number:
477-29-2
Molecular Weight:
547.55
Molecular Formula:
C27H33NO11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Colchicoside is a compound that is the subject of research in the field of natural product chemistry and biochemistry. It is a glycoside associated with plants of the Colchicum family and is studied for its biological activity in cellular models. Research on colchicoside includes its role in modulating microtubule dynamics, as it is related to compounds known to affect tubulin polymerization. This action makes it useful for studying cell division and intracellular transport processes. Furthermore, studies investigate the compound′s potential effects on cellular proliferation and migration, which are critical aspects in the understanding of wound healing and tissue regeneration. In plant biology, colchicoside is also examined for its role in plant defense mechanisms and the ecological interactions between plants and their environment.


Colchicoside (CAS 477-29-2) References

  1. Seasonal and spatial variations of alkaloids in Merendera montana in relation to chemical defense and phenology.  |  Gómez, D., et al. 2003. J Chem Ecol. 29: 1117-26. PMID: 12857025
  2. [Role of colchicoside in the treatment of eczema].  |  Huriez, C. and Desmons, F. 1954. Bull Soc Fr Dermatol Syphiligr. 61: 114-5. PMID: 13199588
  3. [Colchicoside and colchicine. III. Some peculiarities in their powers of optical rotation].  |  BELLET, P. and REGNIER, P. 1952. Ann Pharm Fr. 10: 340-4. PMID: 14953074
  4. The Isolation of Colchicoside, Colchicine and Oil from Colchicum autumnale seed.  |  Popović, M., et al. 1981. Planta Med. 42: 136. PMID: 17401941
  5. Thiocolchicoside exhibits anticancer effects through downregulation of NF-κB pathway and its regulated gene products linked to inflammation and cancer.  |  Reuter, S., et al. 2010. Cancer Prev Res (Phila). 3: 1462-72. PMID: 20978115
  6. Critical review on medicinally potent plant species: Gloriosa superba.  |  Jana, S. and Shekhawat, GS. 2011. Fitoterapia. 82: 293-301. PMID: 21059382
  7. Thiocolchicoside suppresses osteoclastogenesis induced by RANKL and cancer cells through inhibition of inflammatory pathways: a new use for an old drug.  |  Reuter, S., et al. 2012. Br J Pharmacol. 165: 2127-39. PMID: 21955206
  8. Comparison of Seeds of Colchicum speciosum and Gloriosa superba in respect to Colchicine and Colchicoside Contents by RP-LC.  |  Gumustas, M., et al. 2016. Nat Prod Commun. 11: 397-400. PMID: 27169190
  9. Coadministration of a Gloriosa superba extract improves the in vivo antitumoural activity of gemcitabine in a murine pancreatic tumour model.  |  Capistrano I, R., et al. 2016. Phytomedicine. 23: 1434-1440. PMID: 27765363
  10. Tropolone alkaloids from Colchicum kurdicum (Bornm.) Stef. (Colchicaceae) as the potent novel antileishmanial compounds; purification, structure elucidation, antileishmanial activities and molecular docking studies.  |  Azadbakht, M., et al. 2020. Exp Parasitol. 213: 107902. PMID: 32353376
  11. Immunoassays for the quantitative determination of colchicine.  |  Poulev, A., et al. 1994. Planta Med. 60: 77-83. PMID: 8134420
  12. High-performance liquid chromatographic determination of colchicine and colchicoside in colchicum (Colchicum autumnale L.) seeds on a home-made stationary phase.  |  Forni, G. and Massarani, G. 1977. J Chromatogr. 131: 444-7. PMID: 853105
  13. Enzymatic modification of natural compounds with pharmacological properties.  |  Riva, S., et al. 1998. Ann N Y Acad Sci. 864: 70-80. PMID: 9928082

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Colchicoside, 5 mg

sc-495835
5 mg
$150.00