Molecular structure of Colchicine Methanethiosulfonate, CAS Number: 1217821-52-7
Colchicine Methanethiosulfonate (CAS 1217821-52-7)
Application:
Colchicine Methanethiosulfonate is a derfivative of Colchicine
CAS Number:
1217821-52-7
Molecular Weight:
523.62
Molecular Formula:
C24H29NO8S2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Methanethiosulfonate derfivative of Colchicine which is an antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis.
Colchicine Methanethiosulfonate (CAS 1217821-52-7) References
- Tubulin structure and biochemistry. | Ludueña, RF., et al. 1992. Curr Opin Cell Biol. 4: 53-7. PMID: 1558754
- Apoptosis in rat hippocampal dentate gyrus after intraventricular colchicine. | Ceccatelli, S., et al. 1997. Neuroreport. 8: 3779-83. PMID: 9427370
- Microtubule-interfering agents activate c-Jun N-terminal kinase/stress-activated protein kinase through both Ras and apoptosis signal-regulating kinase pathways. | Wang, TH., et al. 1998. J Biol Chem. 273: 4928-36. PMID: 9478937
- Role of the colchicine ring A and its methoxy groups in the binding to tubulin and microtubule inhibition. | Andreu, JM., et al. 1998. Biochemistry. 37: 8356-68. PMID: 9622487
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Colchicine Methanethiosulfonate, 5 mg | sc-217946 | 5 mg | $330.00 |