coilin Antibody (H1): sc-53979

Coilin Antibody (H1) is a mouse monoclonal IgG1 antibody that detects coilin in species reactivity X through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-coilin antibody (H1) plays a crucial role in the study of nuclear coiled bodies, which are small nuclear organelles essential for RNA transcription and processing. Coilin (H1) antibody detects a protein vital for the proper formation of Cajal bodies, as coilin contains a nucleolar localization signal and is a self-associating protein. Coilin monoclonal antibody (H1) recognizes a protein that directly binds to survival motor neuron (SMN) proteins, facilitating the recruitment of SMN complex proteins to Cajal bodies and influencing the assembly of the nucleolus during development. Notably, the N-terminus of coilin harbors the self-associating domain, while the C-terminus regulates the number of Cajal bodies within the cell, highlighting the importance of structural features in cellular organization and function.

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Contains Mercury: All HRP conjugates (including bundle forms) contain thiomersal, a mercury compound. Do not dispose in trash. Dispose as hazardous chemical waste according to local, state and federal regulations.

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The preferred coilin antibody is coilin Antibody (F-7): sc-55594.