Date published: 2025-12-15

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Coenzyme A sodium salt (CAS 55672-92-9)

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Alternate Names:
CoA Na2
Application:
Coenzyme A sodium salt is an essential cofactor in enzymatic acetyl transfer reactions
CAS Number:
55672-92-9
Purity:
≥85%
Molecular Weight:
767.53
Molecular Formula:
C21H36N7O16P3S•xNa
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Coenzyme A sodium salt, referred to as CoA, plays a pivotal role in energy transfer and the metabolism of fatty acids. It serves as a vital coenzyme, encompassing a complex structure consisting of a thiol group, a phosphate group, and an adenosine moiety. Coenzyme A sodium salt holds significant importance in energy metabolism, facilitating the transfer of acetyl groups between metabolic pathways. It is indispensable for the synthesis of fatty acids, cholesterol, and various other compounds. Coenzyme A sodium salt serves as a cofactor in the citric acid cycle.Extensively utilized in research, Coenzyme A sodium salt has contributed to studies exploring metabolic pathways, gene expression regulation, and cellular and molecular processes. Additionally, it has proven valuable in investigations of enzyme kinetics and the examination of coenzyme involvement in the modulation of metabolic pathways.


Coenzyme A sodium salt (CAS 55672-92-9) References

  1. Direct site-selective covalent protein immobilization catalyzed by a phosphopantetheinyl transferase.  |  Wong, LS., et al. 2008. J Am Chem Soc. 130: 12456-64. PMID: 18722432
  2. Effect of polyphenol-rich extract from walnut on diet-induced hypertriglyceridemia in mice via enhancement of fatty acid oxidation in the liver.  |  Shimoda, H., et al. 2009. J Agric Food Chem. 57: 1786-92. PMID: 19256553
  3. The STM4195 gene product (PanS) transports coenzyme A precursors in Salmonella enterica.  |  Ernst, DC. and Downs, DM. 2015. J Bacteriol. 197: 1368-77. PMID: 25645561
  4. LC-MS/MS-based analysis of coenzyme A and short-chain acyl-coenzyme A thioesters.  |  Neubauer, S., et al. 2015. Anal Bioanal Chem. 407: 6681-8. PMID: 26168961
  5. Morphologically and Functionally Distinct Lipid Droplet Subpopulations.  |  Zhang, S., et al. 2016. Sci Rep. 6: 29539. PMID: 27386790
  6. CMOS-compatible biosensor for L-carnitine detection.  |  Andrianova, MS., et al. 2018. Biosens Bioelectron. 119: 48-54. PMID: 30098466
  7. Membrane Fusion Assays for Studying Entry Hepatitis C Virus into Cells.  |  Denolly, S., et al. 2019. Methods Mol Biol. 1911: 219-234. PMID: 30593629
  8. S-Acylation of Proteins.  |  Kordyukova, L., et al. 2019. Methods Mol Biol. 1934: 265-291. PMID: 31256385
  9. Convergent changes in muscle metabolism depend on duration of high-altitude ancestry across Andean waterfowl.  |  Dawson, NJ., et al. 2020. Elife. 9: PMID: 32729830
  10. Discovery of a benzimidazole series as the first highly potent and selective ACSL1 inhibitors.  |  Hayashi, K., et al. 2021. Bioorg Med Chem Lett. 33: 127722. PMID: 33285268
  11. Development of A Continuous Fluorescence-Based Assay for N-Terminal Acetyltransferase D.  |  Ho, YH., et al. 2021. Int J Mol Sci. 22: PMID: 33435607
  12. TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells.  |  Rong, Y., et al. 2021. Elife. 10: PMID: 34409941
  13. Phosphates form spectroscopically dark state assemblies in common aqueous solutions.  |  Straub, JS., et al. 2023. Proc Natl Acad Sci U S A. 120: e2206765120. PMID: 36580589

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Coenzyme A sodium salt, 10 mg

sc-214753
10 mg
$88.00

Coenzyme A sodium salt, 25 mg

sc-214753A
25 mg
$145.00