Molecular structure of Coelenterazine, CAS Number: 55779-48-1
Coelenterazine (CAS 55779-48-1)
See product citations (20)
Alternate Names:
Coelenterazine is also known as Luciferin (Oplophorus).
Application:
Coelenterazine is a chemiluminescent luciferin probe that can be used to detect changes in calcium level and redox status.
CAS Number:
55779-48-1
Purity:
≥95%
Molecular Weight:
423.46
Molecular Formula:
C26H21N3O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Coelenterazine is a cell-permeable aequorin luminophore that acts as a very sensitive and specific chemiluminescence probe of the superoxide anion. Coelenterazine can also be used for detecting changes in intracellular Ca2+ in cells that have been transfected with apoaequorin cDNA. Coelenterazine also acts as a powerful antioxidant. Upon oxidation, Coelenterazine changes to coelenteramide, which is accompanied by blue light of 460 - 470 nm.
Coelenterazine (CAS 55779-48-1) References
- Coelenterazine is a superoxide anion-sensitive chemiluminescent probe: its usefulness in the assay of respiratory burst in neutrophils. | Lucas, M. and Solano, F. 1992. Anal Biochem. 206: 273-7. PMID: 1332545
- Coelenterazine (marine bioluminescent substrate): a source of inspiration for the discovery of novel antioxidants. | Dubuisson, ML., et al. 2005. Drug Dev Ind Pharm. 31: 827-49. PMID: 16305995
- Lighting up bioluminescence with coelenterazine: strategies and applications. | Jiang, T., et al. 2016. Photochem Photobiol Sci. 15: 466-80. PMID: 27009907
- Coelenterazine Analogue with Human Serum Albumin-Specific Bioluminescence. | Nishihara, R., et al. 2020. Bioconjug Chem. 31: 2679-2684. PMID: 33236887
- Azide- and Dye-Conjugated Coelenterazine Analogues for Imaging Mammalian Cells. | Nishihara, R., et al. 2021. Methods Mol Biol. 2274: 111-126. PMID: 34050467
- Luciferase-Specific Coelenterazine Analogues for Optical Cross Talk-Free Bioassays. | Nishihara, R., et al. 2021. Methods Mol Biol. 2274: 127-138. PMID: 34050468
- Chiral deaza-coelenterazine analogs for probing a substrate-binding site in the Ca2+-binding photoprotein aequorin. | Inouye, S., et al. 2021. PLoS One. 16: e0251743. PMID: 34115795
- Synthetic Coelenterazine Derivatives and Their Application for Bioluminescence Imaging. | Jiang, T. and Li, M. 2022. Methods Mol Biol. 2524: 17-36. PMID: 35821460
- Coelenterazine sulfotransferase from Renilla muelleri. | Tzertzinis, G., et al. 2022. PLoS One. 17: e0276315. PMID: 36251663
- Ca2+-Triggered Coelenterazine-Binding Protein Renilla: Expected and Unexpected Features. | Kudryavtsev, AN., et al. 2023. Int J Mol Sci. 24: PMID: 36768474
- Coelenterazine-Type Bioluminescence-Induced Optical Probes for Sensing and Controlling Biological Processes. | Jiang, T., et al. 2023. Int J Mol Sci. 24: PMID: 36982148
- Aequorin-expressing mammalian cell lines used to report Ca2+ mobilization. | Button, D. and Brownstein, M. 1993. Cell Calcium. 14: 663-71. PMID: 7694803
- The origins of marine bioluminescence: turning oxygen defence mechanisms into deep-sea communication tools. | Rees, JF., et al. 1998. J Exp Biol. 201: 1211-21. PMID: 9510532
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Coelenterazine, 1 mg | sc-205904 | 1 mg | $92.00 |