CMV ICP22 Antibody (CH41): sc-69743
- CMV ICP22 Antibody (CH41) is a mouse monoclonal IgG2b provided at 100 µg/ml
- raised against CMV
- recommended for detection of ICP22 of CMV origin by WB and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CMV ICP22 Antibody (CH41). This work is in progress.
CMV ICP22 Antibody (CH41) is a mouse monoclonal IgG2b antibody that detects CMV ICP22 by western blotting (WB) and immunofluorescence (IF). CMV ICP22, also known as HWLF1, is a crucial delayed early nuclear viral protein that plays a significant role in the viral life cycle by repressing both viral and cellular promoters and enhancers, which is essential for regulating gene expression during infection. This repression is vital as it allows the virus to evade the host′s immune response and establish a latent infection, particularly in immunocompromised individuals where CMV can lead to severe complications. The gene encoding CMV ICP22 is located in the S component of the CMV genome, and CMV ICP22 is released from infected cells as a soluble form, highlighting its importance in viral pathogenesis. Anti-CMV ICP22 antibody (CH41) is an invaluable tool for researchers studying CMV infection and its effects on host cellular mechanisms, providing insights into potential therapeutic targets and strategies for managing CMV-related diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CMV ICP22 Antibody (CH41) | sc-69743 | 100 µg/ml | $316.00 |