CMAS Antibody (14W): sc-100486
- CMAS Antibody (14W) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 100 µg/ml
- raised against recombinant CMAS of human origin
- recommended for detection of CMAS of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CMAS Antibody (14W). This work is in progress.
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CMAS Antibody (14W) is a mouse monoclonal IgG2a antibody that detects CMAS in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). CMAS, or cytidine monophosphate N-acetylneuraminic acid synthetase, is a crucial 434 amino acid enzyme that plays a significant role in sialic acid metabolism and is predominantly localized in the nucleus. This evolutionarily conserved protein functions as a homotetramer, catalyzing the conversion of N-acetylneuraminic acid and cytidine triphosphate (CTP) into cytidine 5′-monophosphate N-acetylneuraminic acid (CMP-NeuNAc). The production of CMP-NeuNAc is vital as it serves as an essential donor substrate for sialyltransferases, which are responsible for adding sialic acid to the terminal hydroxyl groups of glycoproteins, polysaccharides, and glycolipids. This post-translational modification is critical for the proper development, structure, and function of animal tissues, influencing various biological processes such as cell signaling, immune response, and tissue development. Anti-CMAS antibody (14W) is an invaluable tool for researchers studying these complex biological pathways and the role of sialic acid in cellular functions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CMAS Antibody (14W) | sc-100486 | 100 µg/ml | $339.00 |