Molecular structure of (+)-Cloprostenol, CAS Number: 54276-21-0
(+)-Cloprostenol (CAS 54276-21-0)
Alternate Names:
(+)-16-m-chlorophenoxy tetranor Prostaglandin F2α
Application:
(+)-Cloprostenol is a synthetic analog of prostaglandin F2&alpha
CAS Number:
54276-21-0
Molecular Weight:
424.9
Molecular Formula:
C22H29ClO6
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
A synthetic analog of prostaglandin F2α (PGF2α), an FP receptor agonist and a potent luteolytic agent in hamsters and rats. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. Cloprostenol is 200 times and 100 times more potent than PGF2α in terminating pregnancy in hamsters and rats, respectively, without having the side effects associated with PGF2α.1
(+)-Cloprostenol (CAS 54276-21-0) References
- Effect of two dosages of d-cloprostenol on intrauterine pressure and uterine motility during dioestrus in experimental cows. | Hirsbrunner, G., et al. 1999. Zentralbl Veterinarmed A. 46: 345-52. PMID: 10481613
- Effect of prostaglandin E2, DL-cloprostenol, and prostaglandin E2 in combination with D-cloprostenol on uterine motility during diestrus in experimental cows. | Hirsbrunner, G., et al. 2003. Anim Reprod Sci. 79: 17-32. PMID: 12853176
- The effect of dose and route of administration of R-cloprostenol on the parturient response of sows. | Kaeoket, K. 2006. Reprod Domest Anim. 41: 472-6. PMID: 16984355
- Synchronization of follicular wave emergence prior to superovulation in Bactrian camel (Camelus bactrianus). | Nikjou, D., et al. 2008. Theriogenology. 69: 491-500. PMID: 18076977
- Luteal function in jennies following PGF(2alpha) treatment 3 days after ovulation. | Carluccio, A., et al. 2008. Theriogenology. 70: 121-5. PMID: 18439666
- Use of Luprostiol and Cloprostenol for induction of parturition in pregnant goats. | Batista, M., et al. 2009. Reprod Domest Anim. 44: 83-7. PMID: 18564313
- Efficacy of homeopathic remedies as prophylaxis of bovine endometritis. | Arlt, S., et al. 2009. J Dairy Sci. 92: 4945-53. PMID: 19762811
- Induction of parturition with aglepristone in the Majorera goat. | Batista, M., et al. 2011. Reprod Domest Anim. 46: 882-8. PMID: 21320179
- Effects of d-cloprostenol dose and corpus luteum age on ovulation, luteal function, and morphology in nonlactating dairy cows with early corpora lutea. | Valldecabres-Torres, X., et al. 2012. J Dairy Sci. 95: 4389-95. PMID: 22818452
- The PGF2α agonists luprostiol and d-cloprostenol reliably induce luteolysis in luteal phase mares without evoking clinical side effects or a stress response. | Kuhl, J., et al. 2016. Anim Reprod Sci. 168: 92-99. PMID: 26963045
- Reproductive parameters of dairy goats after receiving two doses of d-cloprostenol at different intervals. | Maia, ALRS., et al. 2017. Anim Reprod Sci. 181: 16-23. PMID: 28385398
- Effect of the administration of alfaprostol 3 or 6 days after ovulation in jennies: ultrasonographic characteristic of corpora lutea and serum progesterone concentration. | Panzani, D., et al. 2018. Theriogenology. 121: 175-180. PMID: 30165306
- Combined treatment with oestradiol benzoate, d-cloprostenol and oxytocin permits cervical dilation and nonsurgical embryo recovery in ewes. | da Fonseca, JF., et al. 2019. Reprod Domest Anim. 54: 118-125. PMID: 30171642
- Effects of d-cloprostenol administrations with 7.5 and 11.5-day intervals between administrations on pregnancy rates after artificial insemination in estrous cyclic dairy goats. | Bonato, GC., et al. 2019. Anim Reprod Sci. 209: 106172. PMID: 31514929
Activator of:
PGF2alphaR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(+)-Cloprostenol, 1 mg | sc-205259 | 1 mg | $75.00 | |||
(+)-Cloprostenol, 5 mg | sc-205259A | 5 mg | $453.00 |