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Clopidol (CAS 2971-90-6)

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Alternate Names:
3,5-Dichloro-2,6-dimethyl-4-pyridinol
Application:
Clopidol is an antiprotozoal agent
CAS Number:
2971-90-6
Purity:
≥98%
Molecular Weight:
192.04
Molecular Formula:
C7H7Cl2NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Clopidol, an organophosphorus compound, is an antiprotozoal agent. The enzyme acetylcholinesterase is responsible for the degradation of acetylcholine. Through its role as an acetylcholinesterase inhibitor, Clopidol hampers the enzymatic breakdown of acetylcholine. Consequently, an accumulation of acetylcholine occurs within the synaptic cleft, leading to heightened activity of the cholinergic nervous system.


Clopidol (CAS 2971-90-6) References

  1. Determination of nicarbazin and clopidol in poultry feeds by liquid chromatography.  |  Dusi, G., et al. 2000. J Chromatogr A. 882: 79-84. PMID: 10895934
  2. Determination of clopidol residues in chicken tissues by high-performance liquid chromatography-mass spectrometry.  |  Pang, GF., et al. 2000. J Chromatogr A. 882: 85-8. PMID: 10895935
  3. Determination of clopidol residues in chicken tissues by liquid chromatography: part I. Optimization of analytical conditions and comparison with AOAC gas chromatography method.  |  Pang, GF., et al. 2001. J AOAC Int. 84: 1337-42. PMID: 11601450
  4. Determination of clopidol residues in chicken tissues by liquid chromatography: collaborative study.  |  Pang, GF., et al. 2003. J AOAC Int. 86: 685-93. PMID: 14509425
  5. Determination of residual clopidol in chicken muscle by capillary gas chromatography/mass spectrometry.  |  He, L., et al. 2005. J AOAC Int. 88: 1104-7. PMID: 16152927
  6. Relative virulences of a drug-resistant and a drug-sensitive strain of Eimeria acervulina, a coccidium of chickens.  |  Williams, RB. 2006. Vet Parasitol. 135: 15-23. PMID: 16361061
  7. Determination of residual clopidol in chicken muscle by capillary gas chromatography-negative chemical ionization-mass spectrometry.  |  Fang, B., et al. 2009. Anal Sci. 25: 1203-6. PMID: 19822963
  8. Sensitivity of isolates of Eimeria from turkey flocks to the anticoccidial drugs amprolium, clopidol, diclazuril, and monensin.  |  Rathinam, T. and Chapman, HD. 2009. Avian Dis. 53: 405-8. PMID: 19848080
  9. Determination of 20 coccidiostats in milk, duck muscle and non-avian muscle tissue using UHPLC-MS/MS.  |  Clarke, L., et al. 2013. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 30: 958-69. PMID: 23731083
  10. Development of an enzyme-linked immunosorbent assay for detection of clopidol residues in chicken tissues.  |  Jiang, JQ., et al. 2014. J Sci Food Agric. 94: 2295-300. PMID: 24395395
  11. Coccidiostats in milk: development of a multi-residue method and transfer of salinomycin and lasalocid from contaminated feed.  |  Pietruk, K., et al. 2018. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 35: 1508-1518. PMID: 29648988
  12. Microwave method synthesis of magnetic ionic liquid/gold nanoparticles as ultrasensitive SERS substrates for trace clopidol detection.  |  Li, H., et al. 2020. Anal Bioanal Chem. 412: 3063-3071. PMID: 32215690
  13. Restoration of the sensitivity of Eimeria acervulina to anticoccidial drugs in the chicken following use of a live coccidiosis vaccine.  |  Vereecken, M., et al. 2021. Vet Parasitol. 292: 109416. PMID: 33773363
  14. Epidemiological investigation and drug resistance of Eimeria species in Korean chicken farms.  |  Flores, RA., et al. 2022. BMC Vet Res. 18: 277. PMID: 35836230

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Clopidol, 1 g

sc-204694
1 g
$84.00

Clopidol, 5 g

sc-204694A
5 g
$174.00