Clodronate, Disodium Salt (CAS 22560-50-5)
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Clodronate, Disodium salt, belonging to the bisphosphonate class and derived from pyrophosphate, is recognized for its ability to modify bone properties. This compound is a white, crystalline powder that dissolves well in water, with its chemical identity being (dichloromethylene) diphosphonic acid disodium salt. The efficacy of clodronate disodium salt is attributed to its structure, notably the inclusion of two chlorine atoms. It primarily acts by attaching to hydroxyapatite crystals within bone, thereby hindering the activity of osteoclasts, which in turn helps in preventing bone degradation and promotes the enhancement of bone density in situations characterized by elevated bone resorption. Moreover, its role extends to immunomodulation, displaying anti-inflammatory capabilities and influencing the behavior of immune cells such as macrophages, which has sparked interest in its application for studying various immune-related conditions.
Clodronate, Disodium Salt (CAS 22560-50-5) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Clodronate, Disodium Salt, 10 mg | sc-202547 | 10 mg | $122.00 |