CLIC3 Antibody (405): sc-81872
- CLIC3 Antibody (405) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 100 µg/ml
- raised against recombinant CLIC3 of human origin
- recommended for detection of CLIC3 of human origin by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CLIC3 Antibody (405). This work is in progress.
CLIC3 (chloride intracellular channel protein 3) is a member of the highly conserved family of chloride ion channels (CLICs) that function in both soluble and integral membrane forms. Chloride channels regulate cellular traffic of chloride ions, a critical component of all living cells. They are involved in membrane potential stabilization, signal transduction, cell volume regulation and organic solute transport. CLIC3 is found in a variety of tissues but is highly expressed in placenta, brain and heart. CLIC3 predominantly localizes to the nucleus and stimulates chloride ion channel activity when expressed in cells. In addition, CLIC3 interacts with ERK 7 and may play a role in the regulation of cell proliferation. CLIC3 has a short hydrophobic domain suggesting that it must multimerize or associate with other proteins if it functions in a membrane channel. Another possibility is that CLIC3 acts as a channel regulator.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CLIC3 Antibody (405) | sc-81872 | 100 µg/ml | $333.00 |