CLEC-10A Antibody (ER-MP23): sc-56109
- CLEC-10A Antibody (ER-MP23) is a rat monoclonal IgG2a CLEC-10A antibody, cited in 2 publications, provided at 200 µg/ml
- raised against macrophage cell lines of mouse origin
- CLEC-10A Antibody (ER-MP23) is recommended for detection of CLEC-10A of mouse origin by WB, IP, IF and FCM
- Anti-CLEC-10A Antibody (ER-MP23) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CLEC-10A Antibody (ER-MP23). This work is in progress.
CLEC-10A Antibody (ER-MP23) is a rat monoclonal IgG2a antibody that detects CLEC-10A protein of mouse origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). CLEC-10A Antibody (ER-MP23) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CLEC-10A, also known as C-type lectin domain family 10, member A, macrophage galactose and N-acetylgalactosamine-specific lectin, or macrophage asialoglycoprotein-binding protein, plays a crucial role in immune response due to galactose-binding activity and specificity for certain sugars. CLEC-10A is predominantly expressed in macrophages, particularly in mouse lung tissue, where CLEC-10A serves as a unique marker, and CLEC-10A expression is notably intense in skin extracts, indicating a significant presence in dermis and subcutaneous layers. CLEC-10A localization suggests a role in mediating interactions between macrophages and tumor cells, potentially influencing tumor progression and immune evasion. CLEC-10A binding to specific glycoproteins enhances understanding of macrophage function in both normal physiology and disease states, making anti-CLEC-10A antibody (ER-MP23) an essential tool for researchers studying immune responses and macrophage biology.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CLEC-10A Antibody (ER-MP23) References:
- Molecular cloning and expression of cDNA encoding a galactose/N-acetylgalactosamine-specific lectin on mouse tumoricidal macrophages. | Sato, M., et al. 1992. J Biochem. 111: 331-6. PMID: 1587794
- Molecular cloning and sequence analysis of cDNA encoding the macrophage lectin specific for galactose and N-acetylgalactosamine. | Ii, M., et al. 1990. J Biol Chem. 265: 11295-8. PMID: 2358462
- Binding of activated macrophages to tumor cells through a macrophage lectin and its role in macrophage tumoricidal activity. | Oda, S., et al. 1989. J Biochem. 105: 1040-3. PMID: 2768210
- Calcium-dependent conformation of a mouse macrophage calcium-type lectin. Carbohydrate binding activity is stabilized by an antibody specific for a calcium-dependent epitope. | Kimura, T., et al. 1995. J Biol Chem. 270: 16056-62. PMID: 7541793
- Restricted expression of galactose/N-acetylgalactosamine-specific macrophage C-type lectin to connective tissue and to metastatic lesions in mouse lung. | Imai, Y., et al. 1995. Immunology. 86: 591-8. PMID: 8567026
- Unique tissue distribution of a mouse macrophage C-type lectin. | Mizuochi, S., et al. 1997. Glycobiology. 7: 137-46. PMID: 9061372
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CLEC-10A Antibody (ER-MP23) | sc-56109 | 200 µg/ml | $316.00 | |||
CLEC-10A Antibody (ER-MP23) AC | sc-56109 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CLEC-10A Antibody (ER-MP23) HRP | sc-56109 HRP | 200 µg/ml | $316.00 | |||
CLEC-10A Antibody (ER-MP23) FITC | sc-56109 FITC | 200 µg/ml | $330.00 | |||
CLEC-10A Antibody (ER-MP23) PE | sc-56109 PE | 200 µg/ml | $343.00 | |||
CLEC-10A Antibody (ER-MP23) Alexa Fluor® 488 | sc-56109 AF488 | 200 µg/ml | $357.00 | |||
CLEC-10A Antibody (ER-MP23) Alexa Fluor® 546 | sc-56109 AF546 | 200 µg/ml | $357.00 | |||
CLEC-10A Antibody (ER-MP23) Alexa Fluor® 594 | sc-56109 AF594 | 200 µg/ml | $357.00 | |||
CLEC-10A Antibody (ER-MP23) Alexa Fluor® 647 | sc-56109 AF647 | 200 µg/ml | $357.00 | |||
CLEC-10A Antibody (ER-MP23) Alexa Fluor® 680 | sc-56109 AF680 | 200 µg/ml | $357.00 | |||
CLEC-10A Antibody (ER-MP23) Alexa Fluor® 790 | sc-56109 AF790 | 200 µg/ml | $357.00 |