Molecular structure of CL 82198 hydrochloride, CAS Number: 1188890-36-9
CL 82198 hydrochloride (CAS 1188890-36-9)
Application:
CL 82198 hydrochloride is a selective inhibitor of MMP-13
CAS Number:
1188890-36-9
Molecular Weight:
338.83
Molecular Formula:
C17H33N2O3•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
CL 82198 hydrochloride is a selective inhibitor of MMP-13 (89% inhibition at 10 mug/mL) that shows no activity at MMP-1, MMP-9 or TACE. Inhibits in vitro invasion by the human pituitary adenoma cell line HP75.This synthetic amide molecule has attracted considerable attention in scientific research due to its potential applications across diverse fields. Investigations have focused on its suitability for cell culture studies, as well as its capacity to influence the activity of proteins and enzymes.
CL 82198 hydrochloride (CAS 1188890-36-9) References
- Oxidative stress-dependent MMP-13 activity underlies glucose neurotoxicity. | Waldron, AL., et al. 2018. J Diabetes Complications. 32: 249-257. PMID: 29306589
- Transcriptome Profiling of Osteoblasts in a Medaka (Oryzias latipes) Osteoporosis Model Identifies Mmp13b as Crucial for Osteoclast Activation. | Liu, R., et al. 2022. Front Cell Dev Biol. 10: 775512. PMID: 35281094
Inhibitor of:
Cbl-b, and MMP-13.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CL 82198 hydrochloride, 10 mg | sc-203896 | 10 mg | $312.00 | |||
CL 82198 hydrochloride, 50 mg | sc-203896A | 50 mg | $644.00 |