Molecular structure of CKI-7 dihydrochloride, CAS Number: 1177141-67-1
CKI-7 dihydrochloride (CAS 1177141-67-1)
See product citations (5)
Alternate Names:
N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide dihydrochloride
Application:
CKI-7 dihydrochloride is an inhibitor of CK1, SGK, p70 S6 Kinase (S6K1) and MSK1.
CAS Number:
1177141-67-1
Purity:
≥98%
Molecular Weight:
358.67
Molecular Formula:
C11H12ClN3O2S•2HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
A CK1 inhibitor which also inhibits SGK, S6K1 and MSK1. Inhibits SGK as potently as CK1.
CKI-7 dihydrochloride (CAS 1177141-67-1) References
Rena, G., et al. , D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a. EMBO J. Rep. 5, 60-65, (2004)Inhibitor of:
C11orf53, Casein Kinase, casein kinase I epsilon, casein kinase Iα, casein kinase Iδ, casein kinase Iγ1, casein kinase Iγ2, CSNK1A1L, karyopherin β2, MAPKAPK-2, MSK1, p70 S6 Kinase, and SGK.Substrate of:
LTC4 synthase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CKI-7 dihydrochloride, 5 mg | sc-252621 | 5 mg | $280.00 | |||
CKI-7 dihydrochloride, 10 mg | sc-252621A | 10 mg | $320.00 |