Molecular structure of CK-636, CAS Number: 442632-72-6
CK-636 (CAS 442632-72-6)
Alternate Names:
N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide CK-0944636 N-(2-(2-methyl-1H-indol-3-yl)ethyl)thiophene-2-carboxamide CK 636 82XC8RSD8V
CAS Number:
442632-72-6
Molecular Weight:
284.38
Molecular Formula:
C16H16N2OS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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CK-636 (CAS 442632-72-6) References
- Characterization of two classes of small molecule inhibitors of Arp2/3 complex. | Nolen, BJ., et al. 2009. Nature. 460: 1031-4. PMID: 19648907
- The membrane fusion step of vaccinia virus entry is cooperatively mediated by multiple viral proteins and host cell components. | Laliberte, JP., et al. 2011. PLoS Pathog. 7: e1002446. PMID: 22194690
- Small molecules CK-666 and CK-869 inhibit actin-related protein 2/3 complex by blocking an activating conformational change. | Hetrick, B., et al. 2013. Chem Biol. 20: 701-12. PMID: 23623350
- Arp2/3 complex inhibitors adversely affect actin cytoskeleton remodeling in the cultured murine kidney collecting duct M-1 cells. | Ilatovskaya, DV., et al. 2013. Cell Tissue Res. 354: 783-92. PMID: 24036843
- Actin-related protein2/3 complex regulates tight junctions and terminal differentiation to promote epidermal barrier formation. | Zhou, K., et al. 2013. Proc Natl Acad Sci U S A. 110: E3820-9. PMID: 24043783
- Migration of T cells on surfaces containing complex nanotopography. | Kwon, KW., et al. 2013. PLoS One. 8: e73960. PMID: 24069255
- Actin-related protein 2/3 complex-based actin polymerization is critical for male fertility. | Lee, JS., et al. 2015. Andrology. 3: 937-46. PMID: 26223325
- The Association Between WAVE1 and -3 and the ARP2/3 Complex in PC 3 Cells. | Weeks, HP., et al. 2016. Anticancer Res. 36: 1135-42. PMID: 26977009
- Intracellular Trafficking Pathways of Edwardsiella tarda: From Clathrin- and Caveolin-Mediated Endocytosis to Endosome and Lysosome. | Sui, ZH., et al. 2017. Front Cell Infect Microbiol. 7: 400. PMID: 28932708
- Synthesis, Screening and Characterization of Novel Potent Arp2/3 Inhibitory Compounds Analogous to CK-666. | Fokin, AI., et al. 2022. Front Pharmacol. 13: 896994. PMID: 35707404
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CK-636, 10 mg | sc-507565 | 10 mg | $172.00 |