Citreoviridin (CAS 25425-12-1)

Citreoviridin, a mycotoxin produced by several species of the Penicillium genus, including Penicillium citreonigrum, exhibits a fascinating mode of action primarily through its interference with mitochondrial ATPase function. This biochemical interference disrupts the normal process of ATP synthesis, a energy currency in cellular activities, leading to the impairment of energy metabolism within cells. The unique mechanism by which citreoviridin exerts its effects has drawn considerable interest in the field of research, particularly in studies aiming to understand the intricacies of mitochondrial dysfunctions and their consequences on cellular health. By inhibiting the ATPase enzyme, citreoviridin serves as a powerful tool for dissecting the pathways of energy metabolism and elucidating the mechanisms underlying cellular energy homeostasis. Moreover, its role in inducing mitochondrial dysfunction makes it a valuable compound in the study of diseases characterized by altered energy metabolism, providing insights that could lead to the development of novel research methodologies or interventions aimed at mitigating such dysfunctions.