Molecular structure of Citalopram N-Oxide, CAS Number: 63284-72-0
Citalopram N-Oxide (CAS 63284-72-0)
Application:
Citalopram N-Oxide is a metabolite of Citalopram an potential 5-HT selective inhibitor
CAS Number:
63284-72-0
Purity:
≥95%
Molecular Weight:
340.39
Molecular Formula:
C20H21FN2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Citalopram N-Oxide a metabolite
Citalopram N-Oxide (CAS 63284-72-0) References
- In vitro biotransformation of the selective serotonin reuptake inhibitor citalopram, its enantiomers and demethylated metabolites by monoamine oxidase in rat and human brain preparations. | Kosel, M., et al. 2002. Mol Psychiatry. 7: 181-8. PMID: 11840311
- Plasma membrane monoamine transporters: structure, regulation and function. | Torres, GE., et al. 2003. Nat Rev Neurosci. 4: 13-25. PMID: 12511858
- The effect of citalopram on gene expression profile of Alzheimer lymphocytes. | Palotás, A., et al. 2004. Neurochem Res. 29: 1563-70. PMID: 15260135
- Dissection of an allosteric mechanism on the serotonin transporter: a cross-species study. | Neubauer, HA., et al. 2006. Mol Pharmacol. 69: 1242-50. PMID: 16434615
- Serotonergic modulation of locomotion in zebrafish: endogenous release and synaptic mechanisms. | Gabriel, JP., et al. 2009. J Neurosci. 29: 10387-95. PMID: 19692613
- Fate of citalopram during water treatment with O3, ClO2, UV and Fenton oxidation. | Hörsing, M., et al. 2012. Chemosphere. 89: 129-35. PMID: 22704974
- Validated Densitometric TLC-Method for the Simultaneous Analysis of (R)- and (S)-Citalopram and its Related Substances Using Macrocyclic Antibiotic as a Chiral Selector: Application to the Determination of Enantiomeric Purity of Escitalopram. | Soliman, SM. 2012. Int J Biomed Sci. 8: 40-50. PMID: 23675256
- Effect of CYP2D6 genetic polymorphism on the metabolism of citalopram in vitro. | Hu, XX., et al. 2016. Drug Metab Pharmacokinet. 31: 133-8. PMID: 27016952
- Assessment of N-Oxide Formation during Wastewater Ozonation. | Merel, S., et al. 2017. Environ Sci Technol. 51: 410-417. PMID: 27936617
- Metabolic N-Dealkylation and N-Oxidation as Elucidators of the Role of Alkylamino Moieties in Drugs Acting at Various Receptors. | Eh-Haj, BM. 2021. Molecules. 26: PMID: 33805491
- Physiological and Metabolite Alterations Associated with Neuronal Signals of Caenorhabditis elegans during Cronobacter sakazakii Infections. | Muthubharathi, BC., et al. 2021. ACS Chem Neurosci. 12: 4336-4349. PMID: 34704733
- Determination of the enantiomers of citalopram, its demethylated and propionic acid metabolites in human plasma by chiral HPLC. | Rochat, B., et al. 1995. Chirality. 7: 389-95. PMID: 7577348
- Citalopram hydrobromide: degradation product characterization and a validated stability-indicating LC-UV method | Sharma, M., Jawa, P. R., Gill, R. S., & Bansal, G. 2011. Journal of the Brazilian Chemical Society. 22: 836-848.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Citalopram N-Oxide, 1 mg | sc-207444 | 1 mg | $350.00 | |||
Citalopram N-Oxide, 2 mg | sc-207444A | 2 mg | $568.00 | |||
Citalopram N-Oxide, 2 mg | sc-207444A-CW | 2 mg | $659.00 |