Date published: 2025-12-3

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Citalopram N-Oxide (CAS 63284-72-0)

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Application:
Citalopram N-Oxide is a metabolite of Citalopram an potential 5-HT selective inhibitor
CAS Number:
63284-72-0
Purity:
≥95%
Molecular Weight:
340.39
Molecular Formula:
C20H21FN2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Citalopram N-Oxide a metabolite


Citalopram N-Oxide (CAS 63284-72-0) References

  1. In vitro biotransformation of the selective serotonin reuptake inhibitor citalopram, its enantiomers and demethylated metabolites by monoamine oxidase in rat and human brain preparations.  |  Kosel, M., et al. 2002. Mol Psychiatry. 7: 181-8. PMID: 11840311
  2. Plasma membrane monoamine transporters: structure, regulation and function.  |  Torres, GE., et al. 2003. Nat Rev Neurosci. 4: 13-25. PMID: 12511858
  3. The effect of citalopram on gene expression profile of Alzheimer lymphocytes.  |  Palotás, A., et al. 2004. Neurochem Res. 29: 1563-70. PMID: 15260135
  4. Dissection of an allosteric mechanism on the serotonin transporter: a cross-species study.  |  Neubauer, HA., et al. 2006. Mol Pharmacol. 69: 1242-50. PMID: 16434615
  5. Serotonergic modulation of locomotion in zebrafish: endogenous release and synaptic mechanisms.  |  Gabriel, JP., et al. 2009. J Neurosci. 29: 10387-95. PMID: 19692613
  6. Fate of citalopram during water treatment with O3, ClO2, UV and Fenton oxidation.  |  Hörsing, M., et al. 2012. Chemosphere. 89: 129-35. PMID: 22704974
  7. Validated Densitometric TLC-Method for the Simultaneous Analysis of (R)- and (S)-Citalopram and its Related Substances Using Macrocyclic Antibiotic as a Chiral Selector: Application to the Determination of Enantiomeric Purity of Escitalopram.  |  Soliman, SM. 2012. Int J Biomed Sci. 8: 40-50. PMID: 23675256
  8. Effect of CYP2D6 genetic polymorphism on the metabolism of citalopram in vitro.  |  Hu, XX., et al. 2016. Drug Metab Pharmacokinet. 31: 133-8. PMID: 27016952
  9. Assessment of N-Oxide Formation during Wastewater Ozonation.  |  Merel, S., et al. 2017. Environ Sci Technol. 51: 410-417. PMID: 27936617
  10. Metabolic N-Dealkylation and N-Oxidation as Elucidators of the Role of Alkylamino Moieties in Drugs Acting at Various Receptors.  |  Eh-Haj, BM. 2021. Molecules. 26: PMID: 33805491
  11. Physiological and Metabolite Alterations Associated with Neuronal Signals of Caenorhabditis elegans during Cronobacter sakazakii Infections.  |  Muthubharathi, BC., et al. 2021. ACS Chem Neurosci. 12: 4336-4349. PMID: 34704733
  12. Determination of the enantiomers of citalopram, its demethylated and propionic acid metabolites in human plasma by chiral HPLC.  |  Rochat, B., et al. 1995. Chirality. 7: 389-95. PMID: 7577348
  13. Citalopram hydrobromide: degradation product characterization and a validated stability-indicating LC-UV method  |  Sharma, M., Jawa, P. R., Gill, R. S., & Bansal, G. 2011. Journal of the Brazilian Chemical Society. 22: 836-848.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Citalopram N-Oxide, 1 mg

sc-207444
1 mg
$343.00

Citalopram N-Oxide, 2 mg

sc-207444A
2 mg
$557.00

Citalopram N-Oxide, 2 mg

sc-207444A-CW
2 mg
$659.00