Date published: 2026-3-26

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Citalopram-d6 (CAS 1190003-26-9)

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Alternate Names:
1-[3-(Dimethylamino-d6)propyl]-1-(4-fluorophenyl)-1,3-dizohydro-5-isobenzofurancarbonitrile
Application:
Citalopram-d6 is a deuterium-labeled analog of Citalopram
CAS Number:
1190003-26-9
Molecular Weight:
330.43
Molecular Formula:
C20H15D6FN2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Citalopram-d6 is a deuterium-labeled analog of Citalopram (sc-201123). Citalopram is a selective inhibitor of the 5-hydroxytryptamine transporter (serotonin) and therefore is a potent and selective serotonin reuptake inhibitor. Additional studies indicate that Citalopram may be a weak, allosteric modulator of serotonin in a cross-species chimeric study. Studies also indicate that Citalopram is useful for studying gene expression patterns in circulating lymphocytes. In zebrafish, Citalopram is noted to reduce the frequency of NMDA-induced locomotor rhythm involved in swimming behavor.


Citalopram-d6 (CAS 1190003-26-9) References

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  2. The effect of citalopram on gene expression profile of Alzheimer lymphocytes.  |  Palotás, A., et al. 2004. Neurochem Res. 29: 1563-70. PMID: 15260135
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  4. Serotonergic modulation of locomotion in zebrafish: endogenous release and synaptic mechanisms.  |  Gabriel, JP., et al. 2009. J Neurosci. 29: 10387-95. PMID: 19692613
  5. Gas chromatography-tandem mass spectrometry assay for the quantification of four benzodiazepines and citalopram in eleven postmortem rabbit fluids and tissues, with application to animal and human samples.  |  Cartiser, N., et al. 2011. J Chromatogr B Analyt Technol Biomed Life Sci. 879: 2909-18. PMID: 21907645
  6. Quantitative method validation for the analysis of 27 antidepressants and metabolites in plasma with ultraperformance liquid chromatography-tandem mass spectrometry.  |  del Mar Ramírez Fernández, M., et al. 2012. Ther Drug Monit. 34: 11-24. PMID: 22210095
  7. Simultaneous quantification of selective serotonin reuptake inhibitors and metabolites in human plasma by liquid chromatography-electrospray mass spectrometry for therapeutic drug monitoring.  |  Ansermot, N., et al. 2012. J Chromatogr B Analyt Technol Biomed Life Sci. 885-886: 117-30. PMID: 22285965
  8. Enantioselective extraction of (+)-(S)-citalopram and its main metabolites using a tailor-made stir bar chiral imprinted polymer for their LC-ESI-MS/MS quantitation in urine samples.  |  Unceta, N., et al. 2013. Talanta. 116: 448-53. PMID: 24148428
  9. The development and validation of a turbulent flow-liquid chromatography-tandem mass spectrometric method for the simultaneous quantification of citalopram, sertraline, bupropion and hydroxybupropion in serum.  |  Petrides, AK., et al. 2014. Clin Biochem. 47: 73-9. PMID: 25087976
  10. Stereoselective determination of citalopram and desmethylcitalopram in human plasma and breast milk by liquid chromatography tandem mass spectrometry.  |  Weisskopf, E., et al. 2016. J Pharm Biomed Anal. 131: 233-245. PMID: 27606925
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  13. Pharmacokinetic and pharmacodynamic interactions between daridorexant, a dual orexin receptor antagonist, and citalopram in healthy subjects.  |  Berger, B., et al. 2021. Eur Neuropsychopharmacol. 51: 90-104. PMID: 34098518
  14. Concentrations of citalopram and escitalopram in postmortem hair segments.  |  Rygaard, K., et al. 2022. Forensic Sci Int. 336: 111349. PMID: 35660811
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Citalopram-d6, 1 mg

sc-217924
1 mg
$367.00