Date published: 2026-2-7

1-800-457-3801

SCBT Portrait Logo
Seach Input

cis/trans-Nepetalactol (CAS 109215-55-6)

0.0(0)
Write a reviewAsk a question

Datasheets

See product citations (1)

CAS Number:
109215-55-6
Molecular Weight:
168.23
Molecular Formula:
C10H16O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

cis/trans-Nepetalactol exhibits anti-inflammatory and anti-tumor activities due to its ability to modulate various signaling pathways, including the NF-κB and MAPK signaling pathways. It inhibits the production of various pro-inflammatory cytokines, including IL-1β, IL-6, and TNF-α. It also has anti-microbial effects by inhibiting the growth of various microorganisms, including Staphylococcus aureus and Escherichia coli. cis/trans-Nepetalactol has various scientific research applications, including its use as a building block in the synthesis of bioactive compounds. For example, it has been utilized as a starting material for the synthesis of (+)-asperolide A, (+)-asperolide B, and (+)-asperolide C.


cis/trans-Nepetalactol (CAS 109215-55-6) References

  1. Semiochemicals related to the aphid Cinara pilicornis and its host, Picea abies: a method to assign nepetalactone diastereomers.  |  Pettersson, M., et al. 2008. J Chromatogr A. 1180: 165-70. PMID: 18166192
  2. An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis.  |  Geu-Flores, F., et al. 2012. Nature. 492: 138-42. PMID: 23172143
  3. Making iridoids/secoiridoids and monoterpenoid indole alkaloids: progress on pathway elucidation.  |  De Luca, V., et al. 2014. Curr Opin Plant Biol. 19: 35-42. PMID: 24709280
  4. The seco-iridoid pathway from Catharanthus roseus.  |  Miettinen, K., et al. 2014. Nat Commun. 5: 3606. PMID: 24710322
  5. Characterization of 10-hydroxygeraniol dehydrogenase from Catharanthus roseus reveals cascaded enzymatic activity in iridoid biosynthesis.  |  Krithika, R., et al. 2015. Sci Rep. 5: 8258. PMID: 25651761
  6. Identification of iridoid synthases from Nepeta species: Iridoid cyclization does not determine nepetalactone stereochemistry.  |  Sherden, NH., et al. 2018. Phytochemistry. 145: 48-56. PMID: 29091815
  7. Uncoupled activation and cyclization in catmint reductive terpenoid biosynthesis.  |  Lichman, BR., et al. 2019. Nat Chem Biol. 15: 71-79. PMID: 30531909
  8. Biocatalytic Strategies towards [4+2] Cycloadditions.  |  Lichman, BR., et al. 2019. Chemistry. 25: 6864-6877. PMID: 30664302
  9. Chemical convergence between plants and insects: biosynthetic origins and functions of common secondary metabolites.  |  Beran, F., et al. 2019. New Phytol. 223: 52-67. PMID: 30707438
  10. The evolutionary origins of the cat attractant nepetalactone in catnip.  |  Lichman, BR., et al. 2020. Sci Adv. 6: eaba0721. PMID: 32426505
  11. Characterization of Camptotheca acuminata 10-hydroxygeraniol oxidoreductase and iridoid synthase and their application in biological preparation of nepetalactol in Escherichia coli featuring NADP+ - NADPH cofactors recycling.  |  Awadasseid, A., et al. 2020. Int J Biol Macromol. 162: 1076-1085. PMID: 32599240
  12. The characteristic response of domestic cats to plant iridoids allows them to gain chemical defense against mosquitoes.  |  Uenoyama, R., et al. 2021. Sci Adv. 7: PMID: 33523929
  13. Reconstitution of monoterpene indole alkaloid biosynthesis in genome engineered Nicotiana benthamiana.  |  Dudley, QM., et al. 2022. Commun Biol. 5: 949. PMID: 36088516
  14. Biosynthesis of iridoid sex pheromones in aphids.  |  Köllner, TG., et al. 2022. Proc Natl Acad Sci U S A. 119: e2211254119. PMID: 36227916
  15. Monotropein: A comprehensive review of biosynthesis, physicochemical properties, pharmacokinetics, and pharmacology.  |  Wu, M., et al. 2023. Front Pharmacol. 14: 1109940. PMID: 36937894

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

cis/trans-Nepetalactol, 5 mg

sc-506178B
5 mg
$328.00

cis/trans-Nepetalactol, 25 mg

sc-506178
25 mg
$406.00

cis/trans-Nepetalactol, 50 mg

sc-506178A
50 mg
$676.00