Date published: 2026-2-2

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cis-Pinic acid (CAS 61774-58-1)

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Alternate Names:
cis-3-Carboxy-2,2-dimethyl-cyclobutaneacetic acid; cis-3-Carboxy-2,2-dimethylcyclobutaneacetic acid
CAS Number:
61774-58-1
Molecular Weight:
186.21
Molecular Formula:
C9H14O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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cis-Pinic acid exhibits a remarkable ability to interact with the PPARα receptor, a transcription factor known for its role in governing the expression of genes associated with lipid metabolism and inflammation. Upon binding to PPARα, cis-Pinic acid induces a transformative conformational alteration, facilitating its attachment to DNA and subsequently triggering the activation of specific genes. Consequently, this intricate cascade of events promotes enhanced lipid metabolism while simultaneously mitigating inflammatory responses.


cis-Pinic acid (CAS 61774-58-1) References

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  2. Aged particles derived from emissions of coal-fired power plants: the TERESA field results.  |  Kang, CM., et al. 2011. Inhal Toxicol. 23 Suppl 2: 11-30. PMID: 20462390
  3. Mass spectrometric characterization of isomeric terpenoic acids from the oxidation of α-pinene, β-pinene, d-limonene, and Δ3-carene in fine forest aerosol.  |  Yasmeen, F., et al. 2011. J Mass Spectrom. 46: 425-42. PMID: 21438093
  4. Thermodynamics of oligomer formation: implications for secondary organic aerosol formation and reactivity.  |  DePalma, JW., et al. 2013. Phys Chem Chem Phys. 15: 6935-44. PMID: 23549300
  5. Probing the early stages of solvation of cis-pinate dianions by water, acetonitrile, and methanol: a photoelectron spectroscopy and theoretical study.  |  Hou, GL., et al. 2016. Phys Chem Chem Phys. 18: 3628-37. PMID: 26752236
  6. Synergistic O3 + OH oxidation pathway to extremely low-volatility dimers revealed in β-pinene secondary organic aerosol.  |  Kenseth, CM., et al. 2018. Proc Natl Acad Sci U S A. 115: 8301-8306. PMID: 30076229
  7. Physicochemical Properties of Terebic Acid, MBTCA, Diaterpenylic Acid Acetate, and Pinanediol as Relevant α-Pinene Oxidation Products.  |  Kołodziejczyk, A., et al. 2020. ACS Omega. 5: 7919-7927. PMID: 32309701
  8. Toxicological Responses of α-Pinene-Derived Secondary Organic Aerosol and Its Molecular Tracers in Human Lung Cell Lines.  |  Khan, F., et al. 2021. Chem Res Toxicol. 34: 817-832. PMID: 33653028
  9. Aging of α-Pinene Secondary Organic Aerosol by Hydroxyl Radicals in the Aqueous Phase: Kinetics and Products.  |  Witkowski, B., et al. 2023. Environ Sci Technol. 57: 6040-6051. PMID: 37014140

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

cis-Pinic acid, 50 mg

sc-476232
50 mg
$500.00