Date published: 2025-10-14

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cis-Nerolidol (CAS 3790-78-1)

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Alternate Names:
cis-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol
CAS Number:
3790-78-1
Purity:
≥95%
Molecular Weight:
222.37
Molecular Formula:
C15H26O
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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cis-Nerolidol has been utilized in studies exploring natural insect repellent solutions and as a compound with fungicidal capabilities. Research into cis-Nerolidol has also indicated its efficacy against certain insects, including mosquitoes, cockroaches, and flies. it is thought that its ability to interfere with cellular membranes and protein function may underpin its inhibitory effects on cell proliferation and survival. Its antioxidant qualities might also play a role in these observed effects.


cis-Nerolidol (CAS 3790-78-1) References

  1. Characterization of nerolidol biotransformation based on indirect on-line estimation of biomass concentration and physiological state in batch cultures of Aspergillus niger.  |  Hrdlicka, PJ., et al. 2004. Biotechnol Prog. 20: 368-76. PMID: 14763865
  2. Specific involvement of two amino acid residues in cis-nerolidol binding to odorant-binding protein 5 AlinOBP5 in the alfalfa plant bug, Adelphocoris lineolatus (Goeze).  |  Wang, SY., et al. 2013. Insect Mol Biol. 22: 172-82. PMID: 23294484
  3. Assessment of the antioxidant and antiproliferative effects of sesquiterpenic compounds in in vitro Caco-2 cell models.  |  Vinholes, J., et al. 2014. Food Chem. 156: 204-11. PMID: 24629959
  4. Anti-biofilm, anti-hemolysis, and anti-virulence activities of black pepper, cananga, myrrh oils, and nerolidol against Staphylococcus aureus.  |  Lee, K., et al. 2014. Appl Microbiol Biotechnol. 98: 9447-57. PMID: 25027570
  5. Cis-Nerolidol Induces Endoplasmic Reticulum Stress and Cell Death in Human Hepatocellular Carcinoma Cells through Extensive CYP2C19 and CYP1A2 Oxidation.  |  Biazi, BI., et al. 2017. Basic Clin Pharmacol Toxicol. 121: 334-341. PMID: 28256105
  6. Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions.  |  Špičáková, A., et al. 2017. Molecules. 22: PMID: 28338641
  7. New insight into the behaviour modifying activity of two natural sesquiterpenoids farnesol and nerolidol towards Myzus persicae (Sulzer) (Homoptera: Aphididae).  |  Wróblewska-Kurdyk, A., et al. 2020. Bull Entomol Res. 110: 249-258. PMID: 31559933
  8. Phytotoxicity, Morphological, and Metabolic Effects of the Sesquiterpenoid Nerolidol on Arabidopsis thaliana Seedling Roots.  |  Landi, M., et al. 2020. Plants (Basel). 9: PMID: 33053766
  9. Nanoparticles Loaded with Essential Oil from Zanthoxylum riedelianum Engl. Leaves: Characterization and Effects on Bemisia tabaci Middle-East Asia Minor 1.  |  Christofoli, M., et al. 2022. Neotrop Entomol. 51: 761-776. PMID: 35948802
  10. In vitro and in silico analysis of the Anopheles anticholinesterase activity of terpenoids.  |  Rants'o, TA., et al. 2023. Parasitol Int. 93: 102713. PMID: 36455706
  11. Mechanism of cis-Nerolidol-Induced Bladder Carcinoma Cell Death.  |  Glumac, M., et al. 2023. Cancers (Basel). 15: PMID: 36765938
  12. The insecticidal activity of essential oil constituents against pyrethroid-resistant Anopheles funestus (Diptera: Culicidae).  |  Rants'o, TA., et al. 2023. Parasitol Int. 95: 102749. PMID: 36898498
  13. Cis-Nerolidol Inhibits MAP Kinase and NF-κB Signaling Pathways and Prevents Epithelial Tight Junction Dysfunction in Colon Inflammation: In Vivo and In Vitro Studies.  |  Raj, V., et al. 2023. Molecules. 28: PMID: 37049744

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

cis-Nerolidol, 1 ml

sc-227675A
1 ml
$500.00

cis-Nerolidol, 25 mg

sc-227675
25 mg
$215.00