cis-Dichlorobis(triphenylphosphite)platinum(II) (CAS 30053-58-8)

Cis-Dichlorobis(triphenylphosphite)platinum(II), also referred to as cis-DTP, is a coordination compound composed of platinum and the triphenylphosphite ligand, which is an organic compound containing phosphorus. It exists as a white, crystalline solid with a melting point of 190°C. Extensive research has explored the diverse scientific domains where Cis-Dichlorobis(triphenylphosphite)platinum(II) shows promise. In the field of catalysis, Cis-Dichlorobis(triphenylphosphite)platinum(II) has served as a catalyst for various reactions, including alkene hydrogenation and alcohol oxidation. Within materials science, it has been employed as a precursor for synthesizing novel materials such as nanostructured materials and metal-organic frameworks. Although the precise mechanism of action of Cis-Dichlorobis(triphenylphosphite)platinum(II) is not yet fully understood, it is believed to interact with DNA, specifically binding to it. By doing so, it inhibits the activity of topoisomerase II, an enzyme for DNA replication and transcription.