cis-ACPD CAS: 39026-63-6
MF: C7H11NO4
MW: 173.2
A potent structurally rigid agonist of the NMDA receptor.

cis-ACPD (CAS 39026-63-6)

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Alternate Names: (±)-1-Aminocyclopentane-cis-1,3-dicarboxylic acid
Application: cis-ACPD is a potent structurally rigid agonist of the NMDA receptor
CAS Number: 39026-63-6
Molecular Weight: 173.2
Molecular Formula: C7H11NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

cis-ACPD is a potent NMDA agonist and selective group II mGluR agonist with EC50 values of 13, 50, >300 and >300 μM at mGluR-2, mGluR-4, mGluR-1a (mGluR-1) and mGluR-5 respectively. This product contains a 1:1 mixture of (1R,3R)-ACPD.


References

1. McLennan, H. 1983. Prog. Neurobiol. 20: 251-171. PMID: 6142499
2. Olverman, H.J., et al. 1988. Neuroscience. 26: 17-31. PMID: 2901691
3. Schoepp, D.D., et al. 1991. J. Neurochem. 56: 1789-1796. PMID: 1849553
4. Schoepp, D.D., et al. 1999. Neuropharmacology. 38: 1431-1476.

Physical State :
Solid
Solubility :
Soluble in dilute aqueous base. Insoluble in water.
Storage :
Store at 4° C
IC50 :
mGluR-2: EC5050 = 13 µM; mGluR-4: EC5050 = 50 µM; mGluR-1: EC5050 = >300 µM; mGluR-5: EC5050 = >300 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
104766
MDL Number :
MFCD00132879
Beilstein Registry :
4673375
SMILES :
C1C[[email protected]](C[[email protected]@H]1C(=O)O)(C(=O)O)N

Download SDS (MSDS)

Certificate of Analysis

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