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cis-ACPD (CAS 39026-63-6)

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Alternate Names:
(±)-1-Aminocyclopentane-cis-1,3-dicarboxylic acid
Application:
cis-ACPD is a potent structurally rigid agonist of the NMDA receptor
CAS Number:
39026-63-6
Molecular Weight:
173.2
Molecular Formula:
C7H11NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

cis-ACPD is a potent NMDA agonist. Equimolar mixture of (1R,3R)-ACPD


cis-ACPD (CAS 39026-63-6) References

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  2. Carbon monoxide mediates vasodilator effects of glutamate in isolated pressurized cerebral arterioles of newborn pigs.  |  Fiumana, E., et al. 2003. Am J Physiol Heart Circ Physiol. 284: H1073-9. PMID: 12666665
  3. Long-lasting enhancement of metabotropic excitatory amino acid receptor-mediated polyphosphoinositide hydrolysis in the amygdala/pyriform cortex of deep prepiriform cortical kindled rats.  |  Akiyama, K., et al. 1992. Brain Res. 569: 71-7. PMID: 1319260
  4. Mechanisms involved in the cerebrovascular dilator effects of N-methyl-d-aspartate in cerebral cortex.  |  Busija, DW., et al. 2007. Brain Res Rev. 56: 89-100. PMID: 17716743
  5. In vitro and in vivo pharmacology of trans- and cis-(+-)-1-amino-1,3-cyclopentanedicarboxylic acid: dissociation of metabotropic and ionotropic excitatory amino acid receptor effects.  |  Schoepp, DD., et al. 1991. J Neurochem. 56: 1789-96. PMID: 1849553
  6. Coupling of glutamatergic receptors to changes in intracellular Ca2+ in rat cerebellar granule cells in primary culture.  |  Holopainen, I., et al. 1990. J Neurosci Res. 25: 187-93. PMID: 2157031
  7. Functional role of astrocyte glutamate receptors and carbon monoxide in cerebral vasodilation response to glutamate.  |  Parfenova, H., et al. 2012. Am J Physiol Heart Circ Physiol. 302: H2257-66. PMID: 22467311
  8. CORM-A1 prevents blood-brain barrier dysfunction caused by ionotropic glutamate receptor-mediated endothelial oxidative stress and apoptosis.  |  Basuroy, S., et al. 2013. Am J Physiol Cell Physiol. 304: C1105-15. PMID: 23576575
  9. Transient, 5-HT2B receptor-mediated facilitation in neuropathic pain: Up-regulation of PKCγ and engagement of the NMDA receptor in dorsal horn neurons.  |  Aira, Z., et al. 2013. Pain. 154: 1865-1877. PMID: 23769718
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  13. Receptors for the excitatory amino acids in the mammalian central nervous system.  |  McLennan, H. 1983. Prog Neurobiol. 20: 251-71. PMID: 6142499
  14. Transmitter regulation of plateau properties in turtle motoneurons.  |  Svirskis, G. and Hounsgaard, J. 1998. J Neurophysiol. 79: 45-50. PMID: 9425175

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

cis-ACPD, 5 mg

sc-202102
5 mg
$60.00