Molecular structure of cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt, CAS Number: 73167-03-0
cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt (CAS 73167-03-0)
Alternate Names:
5,8,11,14,17-Eicosapentaenoic acid; EPA
Application:
cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt is an inhibitor of 5-LO
CAS Number:
73167-03-0
Purity:
≥99%
Molecular Weight:
324.43
Molecular Formula:
C20H29O2•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt inhibits 5-LO (5-lipoxygenase) and reduces thromboxane A2 production.
cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt (CAS 73167-03-0) References
- Regulation of apoptosis in eicosapentaenoic acid-treated HL-60 cells. | Gillis, RC., et al. 2007. J Surg Res. 137: 141-50. PMID: 17084410
- Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products. | Wada, M., et al. 2007. J Biol Chem. 282: 22254-66. PMID: 17519235
- Polyunsaturated fatty acids and cardiovascular disease: implications for nutrigenetics. | Allayee, H., et al. 2009. J Nutrigenet Nutrigenomics. 2: 140-8. PMID: 19776641
- Genetic variants in the metabolism of omega-6 and omega-3 fatty acids: their role in the determination of nutritional requirements and chronic disease risk. | Simopoulos, AP. 2010. Exp Biol Med (Maywood). 235: 785-95. PMID: 20558833
- The effect of different concentrations of linseed oil or fish oil in the maternal diet on the fatty acid composition and oxidative status of sows and piglets. | Tanghe, S., et al. 2015. J Anim Physiol Anim Nutr (Berl). 99: 938-49. PMID: 25142040
- EPA attenuates ultraviolet radiation-induced downregulation of aquaporin-3 in human keratinocytes. | Jeon, BK., et al. 2015. Arch Pharm Res. 38: 1552-60. PMID: 25269537
- Eicosapentaenoic acid metabolism in brain microvessel endothelium: effect on prostaglandin formation. | Yerram, NR., et al. 1989. J Lipid Res. 30: 1747-57. PMID: 2559136
- EPA-enriched ethanolamine plasmalogen and EPA-enriched phosphatidylethanolamine enhance BDNF/TrkB/CREB signaling and inhibit neuronal apoptosis in vitro and in vivo. | Che, H., et al. 2020. Food Funct. 11: 1729-1739. PMID: 32043504
- Effects of Dietary Supplementation with EPA-enriched Phosphatidylcholine and Phosphatidylethanolamine on Glycerophospholipid Profile in Cerebral Cortex of SAMP8 Mice fed with High-fat Diet. | Zhang, C., et al. 2021. J Oleo Sci. 70: 275-287. PMID: 33456004
- Eicosapentaenoic acid (EPA) exhibits antioxidant activity via mitochondrial modulation. | Xiao, B., et al. 2022. Food Chem. 373: 131389. PMID: 34710690
- EPA-Enriched Phospholipids Alleviate Renal Interstitial Fibrosis in Spontaneously Hypertensive Rats by Regulating TGF-β Signaling Pathways. | Shi, HH., et al. 2022. Mar Drugs. 20: PMID: 35200681
- Comparative Proteomics Reveals Evidence of Enhanced EPA Trafficking in a Mutant Strain of Nannochloropsis oculata. | Wan Razali, WA., et al. 2022. Front Bioeng Biotechnol. 10: 838445. PMID: 35646838
- Eicosapentaenoic acid (EPA) production from microorganisms: a review. | Bajpai, P. and Bajpai, PK. 1993. J Biotechnol. 30: 161-83. PMID: 7764033
Inhibitor of:
5-LO.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt, 5 mg | sc-214735 | 5 mg | $49.00 | |||
cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt, 25 mg | sc-214735A | 25 mg | $192.00 |