cis-10,13,16-Docosatrienoic acid (CAS 18104-42-2)

Cis-10,13,16-Docosatrienoic acid, registered under the CAS number 18104-42-2, is a polyunsaturated fatty acid with a carbon chain of 22 atoms, featuring three cis-configured double bonds at the 10th, 13th, and 16th positions. This configuration classifies it as an omega-6 fatty acid, expanding the usual linoleic and arachidonic acid dominated family. The specific positioning and number of double bonds in cis-10,13,16-Docosatrienoic acid influence its role in membrane fluidity and structure, crucial for cell functionality across diverse biological systems. In research, this fatty acid has been pivotal in studies focused on the impacts of fatty acid chain length and unsaturation level on membrane dynamics, such as phase behavior, permeability, and the function of embedded proteins and receptors. These studies help explain how subtle variations in lipid composition can affect cellular signaling and interaction, offering insights into the fundamental aspects of cell biology. Moreover, cis-10,13,16-Docosatrienoic acid has been used in comparative lipidomics to understand how different species adapt their membrane lipid profiles in response to environmental challenges. This research contributes to broader knowledge on how lipids modulate cellular responses to external stimuli, enhancing our understanding of lipid biochemistry and cellular physiology.