MF: C26H26ClNO5 MW: 467.94 A subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit.
Protein-Interacting Inhibitors, Activators & Substrates
CIQ (CAS 486427-17-2)
CIQ is a subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit
C 26H 26ClNO 5
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For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. *
Certificate of Analysis for lot specific data (including water content).
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CIQ is a subunit-selective potentiator of NMDA receptors containing the NMDAε3 or NMDAε4 subunit. This compound is shown to Increase channel opening efficiency and enhance NMDA receptor responses.
1. Mullasseril, P., et al. 2010. Nat. Commun. 1: 1038-1085. PMID: 20981015
Soluble in DMSO (≥ 10 mg/ml, at warmed to 60 °C), and ethanol (10 mM with sonication).
Store at -20° C
Increases channel opening frequency of recombinant NR2C containing receptors: EC
5050 = 2.7 µM; Increases channel opening frequency of recombinant NR2D containing receptors: EC 5050 = 2.8 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
UN 3077, Class 9, Packing group III
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