Ciprofloxacin-d8 (CAS 1130050-35-9)

Ciprofloxacin-d8 (Cip-d8) is a deuterated variant of ciprofloxacin, belonging to the fluoroquinolone class. It offers enhanced stability compared to ciprofloxacin and is easily detectable due to its fluorescence. It aids in the investigation of protein structure, function, and interactions, while also facilitating the identification and quantification of ciprofloxacin levels in biological samples. In scientific research applications, Ciprofloxacin-d8 finds utility in several areas. Firstly, it contributes to protein studies by enabling the identification and quantification of ciprofloxacin concentrations in biological samples. Secondly, it supports new discovery efforts by facilitating the examination of ciprofloxacin′s binding to target proteins. Moreover, Cip-d8 aids in additional scientific studies, allowing researchers to explore the absorption, distribution, metabolism, and excretion of ciprofloxacin within samples. The mechanism of action of cip-d8 closely resembles that of ciprofloxacin. It acts by inhibiting two enzymes, DNA gyrase and topoisomerase IV, for DNA replication and repair. By blocking the activity of these enzymes, cip-d8 effectively hampers bacterial replication, ultimately leading to bacterial death.