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Cinanserin (CAS 1166-34-3)

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Application:
Cinanserin is a serotonin 5-HT2 antagonist
CAS Number:
1166-34-3
Molecular Weight:
340.5
Molecular Formula:
C20H24N2OS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cinanserin is a serotonin 5-HT2 antagonist1,2.


Cinanserin (CAS 1166-34-3) References

  1. Effect of cinanserin, a serotonin antagonist on ethanol preference in the rat.  |  Geller, I., et al. 1975. Proc West Pharmacol Soc. 18: 141-5. PMID: 1178659
  2. Quipazine-induced head-twitch in mice.  |  Malick, JB., et al. 1977. Pharmacol Biochem Behav. 6: 325-9. PMID: 140381
  3. Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro.  |  Chen, L., et al. 2005. J Virol. 79: 7095-103. PMID: 15890949
  4. Mechanism of ketanserin-induced sympatho-inhibition.  |  Koss, MC. 1991. Eur J Pharmacol. 194: 161-6. PMID: 1676374
  5. Rapid desensitization and resensitization of 5-HT2 receptor mediated phosphatidyl inositol hydrolysis by serotonin agonists in quiescent calf aortic smooth muscle cells.  |  Pauwels, PJ., et al. 1990. Life Sci. 47: 2009-19. PMID: 2273941
  6. Cinanserin reduces plasma extravasation after burn plasma transfer in rats.  |  Hernekamp, JF., et al. 2013. Burns. 39: 1226-33. PMID: 23523219
  7. Tonic immobility and the serotonergic system in chickens: differential blockade of receptors by cyproheptadine and cinanserin.  |  Hennig, CW., et al. 1988. Physiol Behav. 44: 15-20. PMID: 3237811
  8. Synergistic antidepressant- and anxiolytic-like effects of harmaline along with cinanserin in acute restraint stress-treated mice.  |  Mosaffa, S., et al. 2021. Psychopharmacology (Berl). 238: 259-269. PMID: 33190164
  9. The effects of cinanserin, a potent serotonin antagonist, on the acquisition of a running response in the rat.  |  Rosen, AJ. and Cohen, ME. 1973. Neuropharmacology. 12: 501-8. PMID: 4725521
  10. Comparison of chlordiazepoxide, methysergide, and cinanserin as modifiers of punished behavior and as antagonists of N,N-dimethyltryptamine.  |  Winter, JC. 1972. Arch Int Pharmacodyn Ther. 197: 147-59. PMID: 5064096
  11. Receptor binding profile of R 41 468, a novel antagonist at 5-HT2 receptors.  |  Leysen, JE., et al. 1981. Life Sci. 28: 1015-22. PMID: 6261070
  12. Effects of cinanserin and p-chlorophenylalanine and their interaction with d-amphetamine on DRL performance in rats.  |  Mele, PC. and Caplan, MA. 1980. Pharmacol Biochem Behav. 12: 883-91. PMID: 6447298
  13. Protective effect of the serotonin receptor antagonist cinanserin in two canine models of pacing-induced myocardial ischemia.  |  Grover, GJ., et al. 1995. Pharmacology. 50: 286-97. PMID: 7667390

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cinanserin, 10 mg

sc-201110
10 mg
$144.00