Molecular structure of Cimetidine hydrochloride, CAS Number: 70059-30-2
Cimetidine hydrochloride (CAS 70059-30-2)
Alternate Names:
Cimetidine HCl
CAS Number:
70059-30-2
Purity:
≥98%
Molecular Weight:
288.80
Molecular Formula:
C10H17N6S•Cl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Cimetidine hydrochloride is a histamine H2-receptor antagonist that functions by competitively inhibiting the action of histamine at the H2 receptors of the parietal cells in the stomach. This inhibition leads to a diminished volume of gastric secretions, along with a lowered concentration of hydrogen ions. By interfering with the binding of histamine to its receptor, cimetidine hydrochloride effectively decreases the production of stomach acid, which may be useful for studying the regulation of gastric acid secretion. At the molecular level, cimetidine hydrochloride interacts with the histamine H2 receptors, preventing the activation of intracellular signaling pathways that lead to the release of gastric acid.
Cimetidine hydrochloride (CAS 70059-30-2) References
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- Compatibility of cefoperazone sodium and cimetidine hydrochloride in 5% dextrose injection. | Lee, DK., et al. 1991. Am J Hosp Pharm. 48: 111-3. PMID: 2000866
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- Cimetidine blocks testosterone synthesis. | Lardinois, CK. and Mazzaferri, EL. 1985. Arch Intern Med. 145: 920-2. PMID: 4039555
- Stability of cimetidine hydrochloride in admixtures after microwave thawing. | Elliott, GT., et al. 1983. Am J Hosp Pharm. 40: 1002-6. PMID: 6869383
- Effects of cimetidine on the elimination and actions of ethanol. | Feely, J. and Wood, AJ. 1982. JAMA. 247: 2819-21. PMID: 7043008
- The actions of cimetidine hydrochloride and mepyramine maleate in rat adjuvant arthritis. | Al-Haboubi, HA. and Zeitlin, IJ. 1982. Eur J Pharmacol. 78: 175-85. PMID: 7075670
- Cimetidine hydrochloride compatibility. II: room temperature stability in intravenous infusion fluids. | Yuhas, EM., et al. 1981. Am J Hosp Pharm. 38: 879-81. PMID: 7246564
- Cimetidine hydrochloride compatibility with preoperative medications. | Yuhas, EM., et al. 1981. Am J Hosp Pharm. 38: 1173-4. PMID: 7270564
- Cimetidine hydrochloride compatibility. III: Room temperature stability in drug admixtures. | Yuhas, EM., et al. 1981. Am J Hosp Pharm. 38: 1919-22. PMID: 7325173
- Cimetidine hydrochloride compatibility. I: Chemical aspects and room temperature stability in intravenous infusion fluids. | Rosenberg, HA., et al. 1980. Am J Hosp Pharm. 37: 390-2. PMID: 7369222
- Stability and compatibility of anakinra with intravenous cimetidine hydrochloride or famotidine in 0.9% sodium chloride injection. | Nahata, MC., et al. 1995. J Clin Pharm Ther. 20: 97-9. PMID: 7650081
- Stability of cimetidine hydrochloride and of clindamycin phosphate in water for injection stored in glass vials at two temperatures. | Nahata, MC., et al. 1993. Am J Hosp Pharm. 50: 2559-61. PMID: 8122695
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cimetidine hydrochloride, 1 g | sc-495878 | 1 g | $46.00 |