Molecular structure of Cimetidine-d3, CAS Number: 1185237-29-9
Cimetidine-d3 (CAS 1185237-29-9)
Alternate Names:
N-Cyano-N′-methyl-d3-N′′-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidine
Application:
Cimetidine-d3 is a histamine H2-receptor antagonist
CAS Number:
1185237-29-9
Molecular Weight:
255.36
Molecular Formula:
C10H13D3N6S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Cimetidine-d3 is a labeled competitive histamine H2-receptor antagonist that inhibits gastric acid secretion and reduces pepsin output. It has also been shown to inhibit the activity of cytochrome P450 and carbonic anhydrase enzymes. Additionally, cimetidine-d3 has anti-inflammatory and anti-allergic effects. It is used in a variety of laboratory experiments to study the effects of cimetidine on biochemical and physiological processes. Cimetidine-d3 is especially useful in experiments involving mass spectrometry to study the metabolism of cimetidine and its metabolites.
Cimetidine-d3 (CAS 1185237-29-9) References
- Clinical pharmacokinetic drug interaction studies of gabapentin enacarbil, a novel transported prodrug of gabapentin, with naproxen and cimetidine. | Lal, R., et al. 2010. Br J Clin Pharmacol. 69: 498-507. PMID: 20573085
- Seasonal Monitoring of Cardiovascular and Antiulcer Agents' Concentrations in Stream Waters Encompassing a Capital City. | Varga, R., et al. 2013. J Pharm (Cairo). 2013: 753928. PMID: 26555992
- Presence of pharmaceuticals in fish collected from urban rivers in the U.S. EPA 2008-2009 National Rivers and Streams Assessment. | Huerta, B., et al. 2018. Sci Total Environ. 634: 542-549. PMID: 29635196
- Coadministration of probenecid and cimetidine with mirogabalin in healthy subjects: A phase 1, randomized, open-label, drug-drug interaction study. | Tachibana, M., et al. 2018. Br J Clin Pharmacol. 84: 2317-2324. PMID: 29920736
- Distribution and Removal of Pharmaceuticals in Liquid and Solid Phases in the Unit Processes of Sewage Treatment Plants. | Park, J., et al. 2020. Int J Environ Res Public Health. 17: PMID: 31973074
- Renal tubular transporter-mediated interactions between mirogabalin and cimetidine in rats. | Yamamura, N., et al. 2023. Xenobiotica. 53: 114-122. PMID: 36715563
Inhibitor of:
Histamine H2 Receptor.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cimetidine-d3, 1 mg | sc-217898 | 1 mg | $360.00 |