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Cimaterol (CAS 54239-37-1)

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Alternate Names:
Cimaterolum
Application:
Cimaterol is an agonist of the β-AR adrenoreceptor
CAS Number:
54239-37-1
Purity:
≥99%
Molecular Weight:
219.29
Molecular Formula:
C12H17N3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cimaterol is a beta-adrenergic agonist that functions as a stimulant of the beta-adrenergic receptors in cells. It activates these receptors, leading to an increase in the production of cyclic AMP, which in turn activates protein kinase A. This activation of protein kinase A then leads to a cascade of intracellular signaling events, ultimately resulting in the stimulation of lipolysis and the inhibition of protein degradation. Cimaterol′s mechanism of action involves its binding to the beta-adrenergic receptors on the cell membrane, triggering a series of biochemical reactions that modulate cellular metabolism. This chemical′s function is to specifically target and activate the beta-adrenergic receptors, thereby influencing cellular processes related to energy metabolism and protein turnover.


Cimaterol (CAS 54239-37-1) References

  1. Cimaterol reduces beta-adrenergic receptor density in rat skeletal muscles.  |  Kim, YS., et al. 1992. J Anim Sci. 70: 115-22. PMID: 1374751
  2. High-performance liquid chromatographic determination of clenbuterol and cimaterol using post-column derivatization.  |  Courtheyn, D., et al. 1991. J Chromatogr. 564: 537-49. PMID: 1678745
  3. Field-amplified on-line sample stacking for separation and determination of cimaterol, clenbuterol and salbutamol using capillary electrophoresis.  |  Shi, Y., et al. 2006. J Chromatogr A. 1125: 124-8. PMID: 16828108
  4. Cimaterol-induced muscle hypertrophy and altered endocrine status in lambs.  |  Beermann, DH., et al. 1987. J Anim Sci. 65: 1514-24. PMID: 2895097
  5. [Beta adrenergic agonists. Mechanisms of action: lipid mobilization and anabolism].  |  Lafontan, M., et al. 1988. Reprod Nutr Dev (1980). 28: 61-84. PMID: 2895488
  6. Effects of the beta-agonist, cimaterol, on growth, body composition and energy expenditure in rats.  |  Sainz, RD. and Wolff, JE. 1988. Br J Nutr. 60: 85-90. PMID: 2900650
  7. Caged-carvedilol as a new tool for visible-light photopharmacology of β-adrenoceptors in native tissues.  |  Duran-Corbera, A., et al. 2022. iScience. 25: 105128. PMID: 36185381
  8. Structure-activity relationships in further series of amino-halogen substituted phenyl-aminoethanols.  |  Engelhardt, G. 1984. Arzneimittelforschung. 34: 1625-32. PMID: 6152155
  9. The effect of acute and chronic administration of the beta-agonist, cimaterol, on protein synthesis in ovine skin and muscle.  |  Nash, JE., et al. 1994. Br J Nutr. 71: 501-13. PMID: 7912105
  10. The effect of cimaterol on muscle fiber characteristics, capillary supply, and metabolic potentials of longissimus and semitendinosus muscles from young Friesian bulls.  |  Vestergaard, M., et al. 1994. J Anim Sci. 72: 2298-306. PMID: 8002449
  11. Long-term effects of cimaterol in Friesian steers: I. Growth, feed efficiency, and selected carcass traits.  |  Chikhou, FH., et al. 1993. J Anim Sci. 71: 906-13. PMID: 8097508
  12. Long-term effects of cimaterol in Friesian steers: II. Carcass composition and meat quality.  |  Chikhou, FH., et al. 1993. J Anim Sci. 71: 914-22. PMID: 8097509
  13. Function and regulation of the beta 3-adrenoceptor.  |  Strosberg, AD. and Pietri-Rouxel, F. 1996. Trends Pharmacol Sci. 17: 373-81. PMID: 8979772

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cimaterol, 10 mg

sc-203549
10 mg
$115.00

Cimaterol, 50 mg

sc-203549A
50 mg
$440.00