Ciclopirox-d11 (CAS 29342-05-0 (unlabeled))

Ciclopirox-d11, an isotopically labeled derivative of ciclopirox, has gained significant attention in scientific research due to its utility as a tracer compound in pharmacokinetic and metabolic studies. Its deuterium substitution provides a means to track the fate of ciclopirox within biological systems with enhanced precision, allowing researchers to investigate its absorption, distribution, metabolism, and excretion patterns in vivo. By administering ciclopirox-d11 and monitoring the levels of its metabolites using advanced analytical techniques such as mass spectrometry, researchers can explain the metabolic pathways involved in ciclopirox biotransformation and identify potential metabolites with biological activity. Furthermore, ciclopirox-d11 serves as a valuable tool in drug-drug interaction studies, enabling the assessment of potential interactions between ciclopirox and other medications by evaluating their impact on ciclopirox metabolism and pharmacokinetics. This isotopically labeled compound also facilitates the development and validation of analytical methods for quantifying ciclopirox and its metabolites in various biological matrices, contributing to the advancement of pharmacological research aimed at optimizing drug formulations and dosing regimens.