Molecular structure of Cibenzoline succinate, CAS Number: 100678-32-8
Cibenzoline succinate (CAS 100678-32-8)
Alternate Names:
2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole succinate
CAS Number:
100678-32-8
Molecular Weight:
380.44
Molecular Formula:
C18H18N2•C4H6O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Cibenzoline succinate blocks ATP-sensitive K channels in pancreatic and heart cells in the μM concentrations. It has also been shown to interact with the K(ATP) channel pore-forming subunit from the cytoplasmic side and inhibits the delayed rectifier K current [I(Kr)] in sino-atrial node cells. Cibenzoline belongs to the class of benzylisoquinolines This specific form, the succinate salt of cibenzoline, improves the solubility and stability of the compound. Improved solubility can facilitate its use in chemical processes or formulations.
Cibenzoline succinate (CAS 100678-32-8) References
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- Usefulness of venoarterial extracorporeal membranous oxygenation for fatal cibenzoline succinate poisoning. | Sato, H., et al. 2020. Acute Med Surg. 7: e507. PMID: 32431847
- A case report of stomach perforation during automatic mechanical chest compression following pulseless electrical activity due to cibenzoline intoxication. | Itoh, T., et al. 2021. Acute Med Surg. 8: e629. PMID: 33532078
- Roles of IK,ACh for perpetuating atrial fibrillation: Effects of atrial-selective K+ channel inhibitor AVE0118 and class I drugs on the persistent atrial fibrillation canine model. | Kambayashi, R., et al. 2022. J Pharmacol Sci. 149: 175-178. PMID: 35717070
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cibenzoline succinate, 50 mg | sc-362179 | 50 mg | $514.00 |