Chrysamine G Disodium Salt (CAS 6472-91-9)

Chrysamine G Disodium Salt is a synthetic derivative of curcumin, recognized for its bright yellow color and extensive utility in biochemical research, particularly in the study of protein aggregation and binding interactions. Its molecular structure allows it to bind selectively to beta-amyloid plaques, a feature that is leveraged in experimental studies focusing on the aggregation processes of proteins. This specific binding capability of Chrysamine G makes it an invaluable tool for researchers exploring the molecular dynamics and structural organization of amyloid fibers, often found in various models of protein aggregation disorders. In research, this compound is primarily used in fluorescence microscopy and spectroscopy due to its fluorescent properties, enabling detailed visualization and analysis of protein deposits in tissue samples and in vitro systems. The disodium salt form enhances its solubility, making it particularly effective for studies in aqueous environments. Through these applications, Chrysione G Disodium Salt aids in elucidating the pathogenesis of protein misfolding and aggregation, offering insights into the molecular interactions that govern these processes. Additionally, its use extends to environmental science, where it serves as a marker in tracing chemical interactions within biological systems, thereby broadening our understanding of biochemical pathways and molecular ecology.