Molecular structure of Choline chloride, CAS Number: 67-48-1
Choline chloride (CAS 67-48-1)
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Alternate Names:
(2-Hydroxyethyl)trimethylammonium chloride
Application:
Choline chloride is an acyl group acceptor
CAS Number:
67-48-1
Purity:
≥99%
Molecular Weight:
139.62
Molecular Formula:
C5H14NO•Cl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Choline Chloride is an acyl group acceptor and choline acetyltransferase substrate. Choline Chloride, a quaternary ammonium salt, serves as a vital source of the essential nutrient choline, playing a critical role in various biochemical processes. It is predominantly used in research applications for its involvement in the synthesis of the phospholipid phosphatidylcholine and the neurotransmitter acetylcholine, for cell membrane integrity and intercellular communication, respectively. In studies focusing on cellular biology, Choline Chloride is often employed to explore the mechanisms of lipid metabolism and the cholinergic system, owing to its role in methylation reactions and signal transduction pathways.
Choline chloride (CAS 67-48-1) References
- Speciation of copper(II) complexes in an ionic liquid based on choline chloride and in choline chloride/water mixtures. | De Vreese, P., et al. 2012. Inorg Chem. 51: 4972-81. PMID: 22524435
- How polar are choline chloride-based deep eutectic solvents? | Pandey, A., et al. 2014. Phys Chem Chem Phys. 16: 1559-68. PMID: 24305780
- Nanostructure, hydrogen bonding and rheology in choline chloride deep eutectic solvents as a function of the hydrogen bond donor. | Stefanovic, R., et al. 2017. Phys Chem Chem Phys. 19: 3297-3306. PMID: 28085165
- Choline chloride vs choline ionic liquids for starch thermoplasticization. | Decaen, P., et al. 2017. Carbohydr Polym. 177: 424-432. PMID: 28962788
- OPLS Force Field for Choline Chloride-Based Deep Eutectic Solvents. | Doherty, B. and Acevedo, O. 2018. J Phys Chem B. 122: 9982-9993. PMID: 30125108
- Restructuring a Deep Eutectic Solvent by Water: The Nanostructure of Hydrated Choline Chloride/Urea. | Sapir, L. and Harries, D. 2020. J Chem Theory Comput. 16: 3335-3342. PMID: 32223260
- Molecular and Spectroscopic Insights of a Choline Chloride Based Therapeutic Deep Eutectic Solvent. | Saha, M., et al. 2020. J Phys Chem A. 124: 4690-4699. PMID: 32396354
- Polyethylene glycol-based deep eutectic solvents as a novel agent for natural gas sweetening. | Aldawsari, JN., et al. 2020. PLoS One. 15: e0239493. PMID: 32956424
- Recent advances in green solvents for lignocellulosic biomass pretreatment: Potential of choline chloride (ChCl) based solvents. | Yiin, CL., et al. 2021. Bioresour Technol. 333: 125195. PMID: 33932810
- Differences on the impact of water on the deep eutectic solvents betaine/urea and choline/urea. | Abranches, DO., et al. 2021. J Chem Phys. 155: 034501. PMID: 34293900
- In Silico Elucidation of Molecular Picture of Water-Choline Chloride Mixture. | Sarkar, S., et al. 2021. J Phys Chem B. 125: 13212-13228. PMID: 34812630
Inhibitor of:
BHMT2, CBWD6, LPD lipase, and PIG-K.Activator of:
β-1,4-Gal-T6, 2310079F23Rik, 2810422O20Rik, 4832428D23Rik, 5830415F09Rik, AChR α 3, AChR α 7, AChRα9, AChRγ, ADAT2, ADH5, AGPS, AGXT2L1, ALDH1L1, BHMT, BHMT2, CEPT1, Ces1c, ChoK, CHPT1, CIDE-C, cSHMT, cyt19, DIMT1, Dnmt2, ELOVL6, Epigen, Ethanolamine kinase 2, FBP, FIC1, FMO5, Folic Acid, GlyT1, GNPAT, GPAT2, HemT-1, IMP-3, IMPA1, IMPA3, ISYNA1, KIAA1429, LCMT1, LIPI, LPAAT-γ, LPAAT-ζ, MAT I, MAT IIα, MAT IIβ, MBOAT5, METT10D, METTL11A, METTL2, METTL23, METTL2A, METTL2B, METTL5, METTL9, MIBP, MRI1, MTHFD2, MTHFD2L, MTHFSD, MTR, NNMT, NrCAM, NSUN1, NSUN2, NSUN5, OCTL1, PAP-2d, PCIF1, PCMTD2, PCYT2, PEMT, Peroxin 19, PIG-F, PIG-preY, PIG-X, PLD, PPC Synthetase, PRMT1, PRMT2, PRMT3, PSS1, PSS2, RG9MTD2, RNMT, SAHH, SAHH-3, SAMC, sarcosine dehydrogenase, SMS1, SMYD4, SPTLC2, SPTSSA, SULT1C1, Tomt, TRM12, TRMT1, TRMT112, Trmt2b, TRMT5, TRMT6, VAChT, Ythdc1, and YTHDF3.Substrate of:
Choactase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Choline chloride, 10 mg | sc-207430 | 10 mg | $32.00 | |||
Choline chloride, 5 g | sc-207430A | 5 g | $36.00 | |||
Choline chloride, 50 g | sc-207430B | 50 g | $51.00 |