Date published: 2025-12-2

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Cholesta-3,5-diene (CAS 747-90-0)

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Application:
Cholesta-3,5-diene is an oxysterol
CAS Number:
747-90-0
Purity:
≥92%
Molecular Weight:
368.64
Molecular Formula:
C27H44
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cholesta-3,5-diene is a steroidal compound that serves as an important precursor in the biosynthesis of various steroids. In biochemistry research, it is often studied for its role in the complex metabolic pathways that lead to the formation of sterols, including cholesterol. Investigations into cholesta-3,5-diene focus on its conversion by enzymes such as sterol hydroxylases and its participation in the intricate regulatory mechanisms that govern lipid homeostasis. In the field of organic chemistry, cholesta-3,5-diene is explored for its reactivity in chemical synthesis, providing insights into the generation of steroidal derivatives with specific structural features. Additionally, it is relevant in the study of membrane biophysics, as sterols derived from cholesta-3,5-diene influence membrane fluidity and permeability, which are critical factors in cellular function.


Cholesta-3,5-diene (CAS 747-90-0) References

  1. Studies of organic residues from ancient Egyptian mummies using high temperature-gas chromatography-mass spectrometry and sequential thermal desorption-gas chromatography-mass spectrometry and pyrolysis-gas chromatography-mass spectrometry.  |  Buckley, SA., et al. 1999. Analyst. 124: 443-52. PMID: 10605875
  2. Composition of the ventral gland-pad sebum from the Mongolian gerbil, Meriones unguiculatus.  |  Jacob, J. and Green, U. 1977. Z Naturforsch C Biosci. 32: 735-8. PMID: 145112
  3. Cholesterylene, a newly recognized tissue lipid, found at high levels in the cornea.  |  Cenedella, RJ., et al. 1992. Biochem Biophys Res Commun. 186: 1647-55. PMID: 1510688
  4. Gas- and particulate-phase specific tracer and toxic organic compounds in environmental tobacco smoke.  |  Bi, X., et al. 2005. Chemosphere. 61: 1512-22. PMID: 15975627
  5. The Liebermann-Burchard reaction: sulfonation, desaturation, and rearrangment of cholesterol in acid.  |  Xiong, Q., et al. 2007. Lipids. 42: 87-96. PMID: 17393214
  6. Docosahexaenoic acid supplementation fully restores fertility and spermatogenesis in male delta-6 desaturase-null mice.  |  Roqueta-Rivera, M., et al. 2010. J Lipid Res. 51: 360-7. PMID: 19690334
  7. Characterization of Nonpolar Lipids and Selected Steroids by Using Laser-Induced Acoustic Desorption/Chemical Ionization, Atmospheric Pressure Chemical Ionization, and Electrospray Ionization Mass Spectrometry.  |  Jin, Z., et al. 2011. Int J Mass Spectrom. 301: 234-239. PMID: 21528012
  8. Liver fluke-induced hepatic oxysterols stimulate DNA damage and apoptosis in cultured human cholangiocytes.  |  Jusakul, A., et al. 2012. Mutat Res. 731: 48-57. PMID: 22044627
  9. Potential Mechanism of Dermal Wound Treatment With Preparations From the Skin Gel of Arabian Gulf Catfish: A Unique Furan Fatty Acid (F6) and Cholesta-3,5-Diene (S5) Recruit Neutrophils and Fibroblasts to Promote Wound Healing.  |  Al-Hassan, JM., et al. 2020. Front Pharmacol. 11: 899. PMID: 32625093
  10. GC-MS based untargeted metabolomics reveals the metabolic response of earthworm (Eudrilus eugeniae) after chronic combinatorial exposure to three different pesticides.  |  Malla, MA., et al. 2023. Sci Rep. 13: 8583. PMID: 37237073

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cholesta-3,5-diene, 25 mg

sc-211079
25 mg
$173.00

Cholesta-3,5-diene, 100 mg

sc-211079A
100 mg
$520.00