Date published: 2025-10-11

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Cholecalciferol (CAS 67-97-0)

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Alternate Names:
Vitamin D3; Activated 7-dehydrocholesterol; Calciol
Application:
Cholecalciferol is an unhydroxylated form of vitamin D3
CAS Number:
67-97-0
Purity:
≥98%
Molecular Weight:
384.64
Molecular Formula:
C27H44O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cholecalciferol is a naturally occuring form of vitamin D. Reported that upon metabolic activation, Cholecalciferol induces cell differentiation and prevents proliferation of cancer cells. Cholecalciferol is an activator of VDR. Cholecalciferol is converted into its active form, calcitriol, in the liver and kidneys, which then regulates calcium and phosphorus levels in the body.


Cholecalciferol (CAS 67-97-0) References

  1. Cholecalciferol and 25-hydroxycholecalciferol content of chicken egg yolk as affected by the cholecalciferol content of feed.  |  Mattila, P., et al. 1999. J Agric Food Chem. 47: 4089-92. PMID: 10552771
  2. Effect of cholecalciferol-enriched hen feed on egg quality.  |  Mattila, P., et al. 2003. J Agric Food Chem. 51: 283-7. PMID: 12502422
  3. [Vitamin D metabolism].  |  Kulda, V. 2012. Vnitr Lek. 58: 400-4. PMID: 22716179
  4. Phenotypic shift of adipocytes by cholecalciferol and 1α,25 dihydroxycholecalciferol in relation to inflammatory status and calcium content.  |  Zoico, E., et al. 2014. Endocrinology. 155: 4178-88. PMID: 25153146
  5. An in-vitro-in-vivo model for the transdermal delivery of cholecalciferol for the purposes of rodent management.  |  Davies, J. and Ingham, A. 2015. Int J Pharm. 487: 101-9. PMID: 25835266
  6. Comparative Pharmacokinetics of Cholecalciferol in Dogs from 2 Different Oral Formulations Using Corrective Measures to Overcome Interference from Endogenous Cholecalciferol.  |  Patel, H., et al. 2017. Drug Res (Stuttg). 67: 388-395. PMID: 28445901
  7. Is cholecalciferol a potential disease-modifying anti-rheumatic drug for the management of rheumatoid arthritis?  |  Bellan, M., et al. 2020. Clin Exp Rheumatol. 38: 343-349. PMID: 31573472
  8. Cholecalciferol or Calcifediol in the Management of Vitamin D Deficiency.  |  Sosa Henríquez, M. and Gómez de Tejada Romero, MJ. 2020. Nutrients. 12: PMID: 32486496
  9. Vitamin D supplementation: cholecalciferol, calcifediol, and calcitriol.  |  Vieth, R. 2020. Eur J Clin Nutr. 74: 1493-1497. PMID: 32704098
  10. Cholecalciferol (vitamin D3) has a direct protective activity against interleukin 6-induced atrophy in C2C12 myotubes.  |  Teixeira, MA., et al. 2021. Aging (Albany NY). 13: 4895-4910. PMID: 33618332
  11. Effects of supraphysiological vitamin D3 (cholecalciferol) supplement on normal adult rat ovarian functions.  |  Refaat, B. and El-Boshy, M. 2021. Histochem Cell Biol. 155: 655-668. PMID: 33641022
  12. Effect of oral cholecalciferol in a murine model of celiac disease: A dose ranging study.  |  Trasciatti, S., et al. 2022. J Steroid Biochem Mol Biol. 220: 106083. PMID: 35257869
  13. In obese hypertensives cholecalciferol inhibits circulating TH17 cells but not macrophage infiltration on adipose tissue.  |  Santos, C., et al. 2023. Clin Immunol. 247: 109244. PMID: 36706826
  14. Assessing adequacy of cholecalciferol supplementation in chicks using plasma cholecalciferol metabolite concentrations as an indicator.  |  Goff, JP. and Horst, RL. 1995. J Nutr. 125: 1351-7. PMID: 7738694

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cholecalciferol, 1 g

sc-205630
1 g
$70.00

Cholecalciferol, 5 g

sc-205630A
5 g
$160.00

Cholecalciferol, 10 g

sc-205630B
10 g
$290.00