Date published: 2026-4-5

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Chloropyramine hydrochloride (CAS 6170-42-9)

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Alternate Names:
N-p-Chlorobenzyl-N′,N′-dimethyl-N-(2-pyridyl)ethylenediamine
Application:
Chloropyramine hydrochloride is a neurotransmitter related agent for research of drug analysis
CAS Number:
6170-42-9
Molecular Weight:
326.26
Molecular Formula:
C16H20ClN3•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Chloropyramine hydrochloride is a compound that functions as a histamine H1 receptor antagonist. It acts by competitively inhibiting the binding of histamine to its receptor, thereby preventing the activation of the receptor and subsequent signaling cascades. Chloropyramine Hydrochloride targets and blocks the H1 receptor, which is involved in mediating allergic responses and inflammatory processes. By interfering with the histamine-receptor interaction, Chloropyramine hydrochloride effectively mitigates the physiological effects of histamine, such as vasodilation, increased vascular permeability, and smooth muscle contraction. This mechanism of action may be a useful for investigating the role of histamine in various biological processes and for studying the pharmacology of H1 receptor antagonists. Its ability to block histamine signaling provides insights into the molecular pathways underlying allergic reactions and inflammatory conditions.


Chloropyramine hydrochloride (CAS 6170-42-9) References

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  2. Small molecule chloropyramine hydrochloride (C4) targets the binding site of focal adhesion kinase and vascular endothelial growth factor receptor 3 and suppresses breast cancer growth in vivo.  |  Kurenova, EV., et al. 2009. J Med Chem. 52: 4716-24. PMID: 19610651
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  5. The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth.  |  Kurenova, E., et al. 2013. Oncotarget. 4: 1632-46. PMID: 24142503
  6. Allergic reaction to the tetracycline component of Ledermix paste: a case report.  |  Kaufman, AY., et al. 2014. Int Endod J. 47: 1090-7. PMID: 24456195
  7. Pharmacokinetic analysis of the FAK scaffold inhibitor C4 in dogs.  |  Wilton, J., et al. 2016. Eur J Drug Metab Pharmacokinet. 41: 55-67. PMID: 25377246
  8. Enhancing As(V) adsorption and passivation using biologically formed nano-sized FeS coatings on limestone: Implications for acid mine drainage treatment and neutralization.  |  Liu, J., et al. 2017. Chemosphere. 168: 529-538. PMID: 27852449
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Chloropyramine hydrochloride, 1 g

sc-234345
1 g
$20.00