Chlorobimane (CAS 76421-73-3)
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Chlorobimane is a fluorescent dye that is used to label and visualize cellular structures and processes. It functions by selectively binding to glutathione, a key antioxidant molecule within cells. Once bound, Chlorobimane becomes highly fluorescent, allowing track the distribution and activity of glutathione within living cells. Chlorobimane′s mechanism of action involves its ability to undergo a reaction with glutathione, resulting in the formation of a fluorescent adduct. This adduct can then be visualized using fluorescence microscopy, providing insights into the dynamics of glutathione metabolism and its role in cellular function. By targeting glutathione, Chlorobimane is powerful for studying oxidative stress, detoxification pathways, and redox signaling within biological systems.
Chlorobimane (CAS 76421-73-3) References
- Protective roles of glutathione in the toxicity of mercury and cadmium compounds to C6 glioma cells. | Cookson, MR. and Pentreath, VW. 1996. Toxicol In Vitro. 10: 257-64. PMID: 20650204
- High-Content Monitoring of Drug Effects in a 3D Spheroid Model. | Mittler, F., et al. 2017. Front Oncol. 7: 293. PMID: 29322028
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Chlorobimane, 10 mg | sc-211073 | 10 mg | $120.00 |