Chlorobenzene (CAS 108-90-7)

Chlorobenzene, a colorless and volatile liquid with a distinctive aromatic odor, plays a significant role in various applications. This organic compound belongs to the class of aromatic hydrocarbons and finds utility in the production of diverse chemicals like phenols, anilines, and benzaldehyde. Additionally, it serves as a solvent for paints, varnishes, and inks. Within the realm of scientific research, chlorobenzene holds a prominent position. It serves as a reagent in organic synthesis and a versatile solvent for various compounds. Moreover, chlorobenzene acts as a reference compound for determining the structure of organic compounds. Furthermore, it aids in the investigation of benzene and its derivatives′ metabolism and the biodegradation of chlorinated compounds. Upon metabolism, chlorobenzene undergoes transformation into hydroquinone and catechol, which further metabolize to yield hippuric acid. The catalysis of chlorobenzene′s metabolism is facilitated by cytochrome P450 enzymes. It is worth noting that the presence of other compounds, such as ethanol and acetaminophen, can influence the metabolism of chlorobenzene.