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Chloroacetyl-D-Phenylalanine (CAS 137503-97-0)

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Alternate Names:
N-Chloroacetyl-D-phenylalanine
CAS Number:
137503-97-0
Molecular Weight:
241.67
Molecular Formula:
C11H12ClNO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Chloroacetyl-D-phenylalanine holds significant importance as a reagent in organic synthesis. Derived from the amino acid phenylalanine, it serves as a chloroacetyl derivative with wide-ranging applications. Chloroacetyl-D-phenylalanine plays a role in various synthetic processes, particularly in the synthesis of peptides and other organic compounds. Functionally, Chloroacetyl-D-phenylalanine is considered a protecting group in peptide synthesis, effectively reducing the reactivity of amino acid side chains. Additionally, it acts as a leaving group, facilitating the formation of peptide bonds.


Chloroacetyl-D-Phenylalanine (CAS 137503-97-0) References

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  3. Ribosomal Incorporation of Consecutive β-Amino Acids.  |  Katoh, T. and Suga, H. 2018. J Am Chem Soc. 140: 12159-12167. PMID: 30221942
  4. Engineering Translation Components Improve Incorporation of Exotic Amino Acids.  |  Katoh, T. and Suga, H. 2019. Int J Mol Sci. 20: PMID: 30691159
  5. Thermal stability of homologous neutral metalloendopeptidases in thermophilic and mesophilic bacteria: structural considerations.  |  Pangburn, MK., et al. 1976. Experientia Suppl. 26: 19-30. PMID: 820564
  6. Thermolysin and other neutral metalloendopeptidases  |  KA Walsh, Y Burstein, MK Pangburn - Methods in enzymology, 1974 - Elsevier. 1974,. Methods in Enzymology. Volume 34,: Pages 435-440.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Chloroacetyl-D-Phenylalanine, 1 g

sc-285284
1 g
$131.00

Chloroacetyl-D-Phenylalanine, 5 g

sc-285284A
5 g
$345.00