Chloro(2,2prime:6prime,2Prime-terpyridine)platinum(II) chloride dihydrate CAS: 151120-25-1
MF: C15H11Cl2N3Pt•2H2O
MW: 535.28
A spectroscopic tag for proteins and DNA intercalator.

Chloro(2,2′:6′,2″-terpyridine)platinum(II) chloride dihydrate (CAS 151120-25-1)

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Alternate Names: Dichloro(2,2′:6′,2′′-terpyridine)platinum(II) dihydrate
Application: Chloro(2,2′:6′,2″-terpyridine)platinum(II) chloride dihydrate is a spectroscopic tag for proteins and DNA intercalator
CAS Number: 151120-25-1
Purity: ≥98%
Molecular Weight: 535.28
Molecular Formula: C15H11Cl2N3Pt•2H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Chloro(2,2′:6′,2″-terpyridine)platinum(II) chloride dihydrate, also identified as [(terpyr)PtCl]Cl, is a complex of Pt and a terpyridine ligand and a DNA intercalating agent. The characteristic UV-Vis bands of the free [(terpyr)PtCl]Cl compound are modified upon addition to ct-DNA, allowing spectroscopic investigation of this interaction. [(terpyr)PtCl]Cl is demonstrated to retard the mobility of the supercoiled form of pHV14 plasmid in gel electrophoresis and to competitively inhibit the intercalative nucleic acid binding of the Ethidium bromide (sc-203735) dye.


References

1. Jennette, K.W., et al. 1974. Proc. Natl. Acad. Sci. U.S.A. 71: 3839-3843. PMID: 4530265
2. Messori, L., et al. 2005. Bioinorg Chem Appl. 239-253. PMID: 18365102

Appearance :
Powder
Physical State :
Solid
Storage :
Desiccate at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
16211752
MDL Number :
MFCD00149950
SMILES :
C1=CC=NC(=C1)C2=NC(=CC=C2)C3=CC=CC=N3.O.O.Cl[Pt]Cl

Download SDS (MSDS)

Certificate of Analysis

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