Date published: 2025-9-14

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Chlormadinone Acetate (CAS 302-22-7)

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Alternate Names:
17-(Acetyloxy)-6-chloropregna-4,6-diene-3,20-dione; 17-Acetoxy-6-chloro-6-dehydroprogesterone; 6-Chloro-17-acetoxy-4,6-pregnadiene-3,20-dione
Application:
Chlormadinone Acetate is a anti-neoplastic progesteron
CAS Number:
302-22-7
Purity:
≥98%
Molecular Weight:
404.93
Molecular Formula:
C23H29ClO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Chlormadinone acetate is utilized in various fields for its properties as a progesterone receptor agonist. In biological studies, it is used to investigate the role of progesterone in cellular and physiological processes by acting on the progesterone receptor to modulate gene expression and cellular response. Chlormadinone acetate is utilized to study endocrine functions and to explore the mechanisms by which progesterone influences reproductive biology, cellular growth patterns, and differentiation processes. It is applied in the investigation of hormone-responsive tissues and the signaling pathways they engage in. The compound is also of interest in materials science and biochemistry for the synthesis of other complex molecules and for serving as a reference compound in analytical assays.


Chlormadinone Acetate (CAS 302-22-7) References

  1. Chlormadinone acetate as an oral contraceptive.  |  Rao, AP. 1970. J Obstet Gynaecol India. 20: 735-41. PMID: 12254495
  2. Chlormadinone acetate: an oral contraceptive.  |  Ahmad, G. and Ismail, NM. 1967. Pak J Med Res. 7: 216-22. PMID: 12305097
  3. Ethinylestradiol/chlormadinone acetate.  |  Curran, MP. and Wagstaff, AJ. 2004. Drugs. 64: 751-60; discussion 761-2. PMID: 15025547
  4. Evaluation of genotoxic potential of synthetic progestin chlormadinone acetate.  |  Siddique, YH. and Afzal, M. 2004. Toxicol Lett. 153: 221-5. PMID: 15451552
  5. Chlormadinone acetate (CMA) in oral contraception--a new opportunity.  |  Bouchard, P. 2005. Eur J Contracept Reprod Health Care. 10 Suppl 1: 7-11. PMID: 16356876
  6. Profile of the progesterone derivative chlormadinone acetate - pharmocodynamic properties and therapeutic applications.  |  Druckmann, R. 2009. Contraception. 79: 272-81. PMID: 19272496
  7. Ethinylestradiol/Chlormadinone acetate: dermatological benefits.  |  Guerra-Tapia, A. and Sancho Pérez, B. 2011. Am J Clin Dermatol. 12 Suppl 1: 3-11. PMID: 21895044
  8. Clinical utility of chlormadinone acetate (Lutoral™) in frozen-thawed embryo transfer with hormone replacement.  |  Asada, Y., et al. 2019. Reprod Med Biol. 18: 290-295. PMID: 31312109
  9. Prospective study of fertility-sparing treatment with chlormadinone acetate for endometrial carcinoma and atypical hyperplasia in young women.  |  Ouasti, S., et al. 2022. Int J Gynaecol Obstet. 157: 452-457. PMID: 34558063
  10. Chlormadinone acetate and its effect on the hemostatic mechanism.  |  Wodzicki, AM. and Coopland, AT. 1972. Can Med Assoc J. 107: 38-41. PMID: 4114470
  11. Dissappearance of 1 alpha-3H-chlormadinone acetate from the plasma of women.  |  Dugwekar, YG., et al. 1973. Contraception. 7: 27-45. PMID: 4134033
  12. The action of chlormadinone acetate (6-chloro-delta6-dehydro-17alpha-acetoxyprogesterone) upon experimentally induced ovulation in the rabbit.  |  Harris, GW. and Sherratt, RM. 1969. J Physiol. 203: 59-66. PMID: 4186126
  13. Contraception with chlormadinone acetate in woman with previous contraceptive jaundice.  |  Thompson, RP. and Williams, R. 1970. Br Med J. 1: 152-3. PMID: 4189931
  14. [The in vivo metabolism of chlormadinone acetate in guinea pig and the uptake of testosterone-3 H and chlormadinone acetate-3 H in prostate of castrated male rat (author's transl)].  |  Tanaka, S., et al. 1980. Nihon Naibunpi Gakkai Zasshi. 56: 1116-29. PMID: 6158464

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Chlormadinone Acetate, 10 mg

sc-211070
10 mg
$133.00